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__NOTOC__
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{{Hairy cell leukemia}}
{{Hairy cell leukemia}}
{{CMG}}
{{CMG}}; {{AE}} {{HL}}; {{GRR}} {{Nat}}
 
==Overview==
==Overview==
 
[[Hairy cell leukemia]] is found to approximately comprise 2% of all [[Leukemia|leukemias]] in the United States. The [[Incidence (epidemiology)|incidence]] of [[hairy cell leukemia]] is approximately 3.2 per 1,000,000 individuals in the United States. The [[incidence]] of [[hairy cell leukemia]] increases with age. Males are more commonly affected with hairy cell [[leukemia]] than females.
==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
===Prevalence===
* It is uncommon, representing about 2% of all leukemias, or less than a total of 2000 new cases diagnosed each year in the North America and Western Europe combined.
* [[Hairy cell leukemia]] is considered one of the least common types of leukemias in the United States.<ref name="pmid29763020">{{cite journal |vauthors=Naing PT, Acharya U |title= |journal= |volume= |issue= |pages= |date= |pmid=29763020 |doi= |url=}}</ref>
 
* [[Hairy cell leukemia]] is found to approximately comprise 2% of all leukemias in the United States.<ref name="pmid266148954">{{cite journal |vauthors=Tadmor T, Polliack A |title=Epidemiology and environmental risk in hairy cell leukemia |journal=Best Pract Res Clin Haematol |volume=28 |issue=4 |pages=175–9 |date=December 2015 |pmid=26614895 |doi=10.1016/j.beha.2015.10.014 |url=}}</ref>
===Incidence===
* The incidence of [[hairy cell leukemia]] is approximately 3.2 per 1,000,000 individuals in the United States.<ref name="pmid16150940">{{cite journal |vauthors=Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, Linet MS |title=Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001 |journal=Blood |volume=107 |issue=1 |pages=265–76 |date=January 2006 |pmid=16150940 |pmc=1895348 |doi=10.1182/blood-2005-06-2508 |url=}}</ref><ref name="pmid21122460">{{cite journal |vauthors=Teodorescu M, Engebjerg MC, Johansen P, Nørgaard M, Gregersen H |title=Incidence, risk of infection and survival of hairy cell leukaemia in Denmark |journal=Dan Med Bull |volume=57 |issue=12 |pages=A4216 |date=December 2010 |pmid=21122460 |doi= |url=}}</ref><ref name="pmid266148953">{{cite journal |vauthors=Tadmor T, Polliack A |title=Epidemiology and environmental risk in hairy cell leukemia |journal=Best Pract Res Clin Haematol |volume=28 |issue=4 |pages=175–9 |date=December 2015 |pmid=26614895 |doi=10.1016/j.beha.2015.10.014 |url=}}</ref>
* For the past 30 years, the incidence of [[hairy cell leukemia]] has been relatively constant.
===Age===
===Age===
* Most patients are white males over the age of 50, although it has been diagnosed in at least one teenager.
* The incidence of [[hairy cell leukemia]] increases with age.
* The average age range at diagnosis of [[hairy cell leukemia]] is 50 to 55 years.<ref name="pmid297630202">{{cite journal |vauthors=Naing PT, Acharya U |title= |journal= |volume= |issue= |pages= |date= |pmid=29763020 |doi= |url=}}</ref><ref name="pmid266148952">{{cite journal |vauthors=Tadmor T, Polliack A |title=Epidemiology and environmental risk in hairy cell leukemia |journal=Best Pract Res Clin Haematol |volume=28 |issue=4 |pages=175–9 |date=December 2015 |pmid=26614895 |doi=10.1016/j.beha.2015.10.014 |url=}}</ref>


===Gender===
===Gender===
* Men are four to five times more likely to develop hairy cell leukemia than women.<ref>{{cite web |url=http://www.pennhealth.com/ency/article/000592.htm |title=Hairy cell leukemia |accessdate=2007-09-07 |format= |work=}}</ref> It does not appear to be hereditary, although occasional familial cases have been reported,<ref>{{cite web |url=http://cat.inist.fr/?aModele=afficheN&cpsidt=4680401 |title=Three cases of familial hairy cell leukemia |accessdate=2007-09-07 |format= |work=}}</ref> usually showing a common HLA type.
* Males are more commonly affected with [[hairy cell leukemia]] than females.
* The male to female ratio is approximately 4 to 1.<ref name="pmid297630203">{{cite journal |vauthors=Naing PT, Acharya U |title= |journal= |volume= |issue= |pages= |date= |pmid=29763020 |doi= |url=}}</ref>
===Race===
* [[Hairy cell leukemia]] usually affects individuals of the Caucasian race.<ref name="pmid18477040">{{cite journal |vauthors=Dores GM, Matsuno RK, Weisenburger DD, Rosenberg PS, Anderson WF |title=Hairy cell leukaemia: a heterogeneous disease? |journal=Br. J. Haematol. |volume=142 |issue=1 |pages=45–51 |date=July 2008 |pmid=18477040 |pmc=4009349 |doi=10.1111/j.1365-2141.2008.07156.x |url=}}</ref>
* Asian and African American individuals are less likely to develop [[hairy cell leukemia]].<ref name="pmid26614895">{{cite journal |vauthors=Tadmor T, Polliack A |title=Epidemiology and environmental risk in hairy cell leukemia |journal=Best Pract Res Clin Haematol |volume=28 |issue=4 |pages=175–9 |date=December 2015 |pmid=26614895 |doi=10.1016/j.beha.2015.10.014 |url=}}</ref>


==References==
==References==
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Latest revision as of 17:20, 8 April 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]

Overview

Hairy cell leukemia is found to approximately comprise 2% of all leukemias in the United States. The incidence of hairy cell leukemia is approximately 3.2 per 1,000,000 individuals in the United States. The incidence of hairy cell leukemia increases with age. Males are more commonly affected with hairy cell leukemia than females.

Epidemiology and Demographics

Prevalence

Incidence

Age

Gender

  • Males are more commonly affected with hairy cell leukemia than females.
  • The male to female ratio is approximately 4 to 1.[8]

Race

References

  1. ↑ Naing PT, Acharya U. PMID 29763020. Missing or empty |title= (help)
  2. ↑ Tadmor T, Polliack A (December 2015). "Epidemiology and environmental risk in hairy cell leukemia". Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.
  3. ↑ Morton LM, Wang SS, Devesa SS, Hartge P, Weisenburger DD, Linet MS (January 2006). "Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001". Blood. 107 (1): 265–76. doi:10.1182/blood-2005-06-2508. PMC 1895348. PMID 16150940.
  4. ↑ Teodorescu M, Engebjerg MC, Johansen P, Nørgaard M, Gregersen H (December 2010). "Incidence, risk of infection and survival of hairy cell leukaemia in Denmark". Dan Med Bull. 57 (12): A4216. PMID 21122460.
  5. ↑ Tadmor T, Polliack A (December 2015). "Epidemiology and environmental risk in hairy cell leukemia". Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.
  6. ↑ Naing PT, Acharya U. PMID 29763020. Missing or empty |title= (help)
  7. ↑ Tadmor T, Polliack A (December 2015). "Epidemiology and environmental risk in hairy cell leukemia". Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.
  8. ↑ Naing PT, Acharya U. PMID 29763020. Missing or empty |title= (help)
  9. ↑ Dores GM, Matsuno RK, Weisenburger DD, Rosenberg PS, Anderson WF (July 2008). "Hairy cell leukaemia: a heterogeneous disease?". Br. J. Haematol. 142 (1): 45–51. doi:10.1111/j.1365-2141.2008.07156.x. PMC 4009349. PMID 18477040.
  10. ↑ Tadmor T, Polliack A (December 2015). "Epidemiology and environmental risk in hairy cell leukemia". Best Pract Res Clin Haematol. 28 (4): 175–9. doi:10.1016/j.beha.2015.10.014. PMID 26614895.


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