Adrenal atrophy causes: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Adrenal atrophy}} | {{Adrenal atrophy}} | ||
{{CMG}}; {{AE}} {{MHP}} | |||
==Overview== | |||
Adrenal atrophy may be caused by a loss of [[ACTH]] and trophic support of the [[adrenal]] [[cortex]] or direct damage to the tissue. | |||
==Causes== | |||
*Adrenal atrophy may be caused by prolonged glucocorticoid therapy or a functional [[adrenocortical neoplasm]] in the same or contralateral gland, which secondarily results in decreased adrenocorticotropic hormone (ACTH) levels. | |||
*Atrophy can also result from more direct ACTH deficiency, such as abnormal pituitary function. | |||
*Cortical atrophy can also be a direct effect of exogenous toxicants that interfere with normal adrenocortical steroidogenesis and/or the physiologic effects of the [[renin-angiotensin]] system on the adrenal. | |||
*Because of the complex physiologic interactions of [[hypothalamus]], [[pituitary]], [[thyroid]], and [[gonads]] with the adrenal gland, other exogenous toxicants and experimental manipulations that directly damage these tissues or modulate their secretory functions can result in secondary effects in the adrenal cortex, including atrophy.<ref name="pmid11215683">{{cite journal |vauthors=Rosol TJ, Yarrington JT, Latendresse J, Capen CC |title=Adrenal gland: structure, function, and mechanisms of toxicity |journal=Toxicol Pathol |volume=29 |issue=1 |pages=41–8 |date=2001 |pmid=11215683 |doi=10.1080/019262301301418847 |url=}}</ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 01:58, 10 June 2022
|
Adrenal atrophy Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Adrenal atrophy causes On the Web |
|
American Roentgen Ray Society Images of Adrenal atrophy causes |
|
Risk calculators and risk factors for Adrenal atrophy causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Hadipour, M.D.[2]
Overview
Adrenal atrophy may be caused by a loss of ACTH and trophic support of the adrenal cortex or direct damage to the tissue.
Causes
- Adrenal atrophy may be caused by prolonged glucocorticoid therapy or a functional adrenocortical neoplasm in the same or contralateral gland, which secondarily results in decreased adrenocorticotropic hormone (ACTH) levels.
- Atrophy can also result from more direct ACTH deficiency, such as abnormal pituitary function.
- Cortical atrophy can also be a direct effect of exogenous toxicants that interfere with normal adrenocortical steroidogenesis and/or the physiologic effects of the renin-angiotensin system on the adrenal.
- Because of the complex physiologic interactions of hypothalamus, pituitary, thyroid, and gonads with the adrenal gland, other exogenous toxicants and experimental manipulations that directly damage these tissues or modulate their secretory functions can result in secondary effects in the adrenal cortex, including atrophy.[1]
References
- ↑ Rosol TJ, Yarrington JT, Latendresse J, Capen CC (2001). "Adrenal gland: structure, function, and mechanisms of toxicity". Toxicol Pathol. 29 (1): 41–8. doi:10.1080/019262301301418847. PMID 11215683.