Methemoglobinemia classification: Difference between revisions
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{{Methemoglobinemia }} | {{Methemoglobinemia }} | ||
{{CMG}} | {{CMG}}; {{AE}}{{AKS}} | ||
==Overview== | ==Overview== | ||
* | Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia. | ||
* | |||
==Classification== | |||
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia. | |||
'''Congenital (Hereditary) Methemoglobinemia''' | |||
*There are three main congenital conditions that lead to methemoglobinemia: | |||
1.[[Cytochrome b5 reductase deficiency]] and [[pyruvate kinase deficiency]]<ref>{{Haematologia (Budap). 1982 Dec;15(4):389-99. Enzymopenic hereditary methemoglobinemia. Jaffé ER. pmid=PMID: 6764628}}</ref> | |||
2.[[G6PD deficiency]] | |||
3.Presence of [[abnormal hemoglobin]] ([[Hb M]]) | |||
'''Acquired or Acute Methemoglobinemia''' | |||
*The most common causes are different [[oxidant drugs]], [[toxins]] and [[chemicals]].<ref>{{Med Toxicol. 1986 Jul-Aug;1(4):253-60. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Hall AH, Kulig KW, Rumack BH.pmid=PMID: 3537620}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Latest revision as of 20:36, 31 July 2018
Methemoglobinemia Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.
Overview
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia.
Classification
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia.
Congenital (Hereditary) Methemoglobinemia
- There are three main congenital conditions that lead to methemoglobinemia:
1.Cytochrome b5 reductase deficiency and pyruvate kinase deficiency[1]
3.Presence of abnormal hemoglobin (Hb M)
Acquired or Acute Methemoglobinemia
- The most common causes are different oxidant drugs, toxins and chemicals.[2]
References
- ↑ Template:Haematologia (Budap). 1982 Dec;15(4):389-99. Enzymopenic hereditary methemoglobinemia. Jaffé ER. pmid=PMID: 6764628
- ↑ Template:Med Toxicol. 1986 Jul-Aug;1(4):253-60. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Hall AH, Kulig KW, Rumack BH.pmid=PMID: 3537620