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__NOTOC__ | __NOTOC__ | ||
{{Lymphocytopenia}} | {{Lymphocytopenia}} | ||
{{CMG}} {{AE}} {{LRO}} | |||
==Overview== | |||
Common causes of lymphocytopenia include side effects of drugs that cause [[platelet]] changes. Additional common causes include congenital and acquired [[hematological]] conditions. | |||
==Causes== | |||
===Common Causes=== | |||
*[[Aclarubicin]] | |||
*[[Adenosine deaminase deficiency]] | |||
*[[Alefacept]] | |||
*[[Alemtuzumab]] | |||
*[[Antithymocyte globulin]] | |||
*[[Aplastic anemia]] | |||
*[[Bendamustine]] | |||
*[[Blinatumomab]] | |||
*[[Cabozantinib]] | |||
*[[Chemotherapy]] | |||
*[[Chloramphenicol]] | |||
*[[Cladribine]] | |||
*[[Common variable hypogammaglobulinaemia]] | |||
*[[Corticosteroids]] | |||
*[[De vaal syndrome]] | |||
*[[Dinutuximab]] | |||
*[[Doxorubicin]] | |||
*[[Elotuzumab]] | |||
*[[Eribulin]] | |||
*[[Everolimus]] | |||
*[[Exemestane]] | |||
*[[Fludarabine]] | |||
*[[Hodgkin's disease]] | |||
*[[Human granulocytic ehrlichiosis]] | |||
*[[Human monocytotropic ehrlichiosis]] | |||
*[[Idarubicin]] | |||
*[[Idelalisib]] | |||
*[[Interferon beta]] | |||
*[[Ixabepilone]] | |||
*[[Legionella pneumophila]] | |||
*[[Legionella pneumophila]] | |||
*[[Leukemia]] | |||
*[[Linezolid]] | |||
*[[Lorcaserin]] | |||
*[[Lymphangiectasis]] | |||
*[[Olaparib]] | |||
*[[Olsalazine]] | |||
*[[Omacetaxine mepesuccinate]] | |||
*[[Oxaliplatin]] | |||
*[[Pamidronate]] | |||
*[[Pancytopenia]] | |||
*[[Pazopanib]] | |||
*[[Pentostatin]] | |||
*[[Rituximab]] | |||
*[[Saxagliptin]] | |||
*[[Schimke immunoosseous dysplasia]] | |||
*[[Sorafenib]] | |||
*[[Sunitinib malate]] | |||
*[[Temsirolimus]] | |||
*[[Vinblastine]] | |||
*[[Waldmann disease]] | |||
*[[Wiskott-aldrich syndrome]] | |||
===Causes by Organ System=== | |||
{|style="width:80%; height:100px" border="1" | |||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" |'''Cardiovascular''' | |||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes | |||
|- | |||
|bgcolor="LightSteelBlue"| '''Chemical/Poisoning''' | |||
|bgcolor="Beige"| [[Dimethyl fumarate]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Dental''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Dermatologic''' | |||
|bgcolor="Beige"| [[Aplasia cutis congenital]], [[Cartilage hair hypoplasia]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Drug Side Effect''' | |||
|bgcolor="Beige"|[[Aclarubicin]], [[Alefacept]], [[Alemtuzumab]], [[Bendamustine]], [[Blinatumomab]], [[Cabozantinib]], [[Chemotherapy]], [[Chloramphenicol]], [[Cladribine]], [[Corticosteroids]], [[Dinutuximab]], [[Doxorubicin]], [[Elotuzumab]], [[Eribulin]], [[Everolimus]], [[Exemestane]], [[Fludarabine]], [[Idarubicin]], [[Idelalisib]], [[Ixabepilone]], [[Legionella pneumophila]], [[Linezolid]], [[Lorcaserin]], [[Olaparib]], [[Olsalazine]], [[Omacetaxine mepesuccinate]], [[Oxaliplatin]], [[Pamidronate]], [[Pazopanib]], [[Pentostatin]], [[Rituximab]], [[Saxagliptin]], [[Sorafenib]], [[Sunitinib malate]], [[Temsirolimus]], [[Vinblastine]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Ear Nose Throat''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Endocrine''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Environmental''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Gastroenterologic''' | |||
|bgcolor="Beige"| [[Intestinal lymphangiectasis]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Genetic''' | |||
|bgcolor="Beige"| [[Mckusick type metaphyseal chondrodysplasia]], [[Purine nucleoside phosphorylase (pnp) deficiency]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Hematologic''' | |||
|bgcolor="Beige"| [[Adenosine deaminase deficiency]], [[Antithymocyte globulin]], [[Aplastic anemia]], [[Common variable hypogammaglobulinaemia]], [[De vaal syndrome]], [[Hodgkin's disease]], [[Human granulocytic ehrlichiosis]], [[Human monocytotropic ehrlichiosis]], [[Interferon beta]], [[Legionella pneumophila]], [[Leukemia]], [[Lymphangiectasis]], [[Pancytopenia]], [[Schimke immunoosseous dysplasia]], [[Waldmann disease]], [[Wiskott-aldrich syndrome]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Iatrogenic''' | |||
|bgcolor="Beige"| [[Chemotherapy]], [[Radiation therapy]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Infectious Disease''' | |||
|bgcolor="Beige"| [[Acute viral nasopharyngitis]], [[Aids]], [[Epstein-barr virus, chronic]], [[Hiv-1 disease]], [[Human granulocytic ehrlichiosis]], [[Human monocytotropic ehrlichiosis]], [[Influenza]], [[Tuberculosis]], [[Typhoid fever]], [[Viral hepatitis]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Musculoskeletal/Orthopedic''' | |||
|bgcolor="Beige"| [[Myelodysplastic syndrome]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Neurologic''' | |||
|bgcolor="Beige"| [[Ataxia telangiectasia]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Nutritional/Metabolic''' | |||
|bgcolor="Beige"| [[Malnutrition]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Obstetric/Gynecologic''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Oncologic''' | |||
|bgcolor="Beige"| [[Leukemia]], [[Myelodysplastic syndrome]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Ophthalmologic''' | |||
|bgcolor="Beige"| [[Reticular dysgenesis]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Overdose/Toxicity''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Psychiatric''' | |||
|bgcolor="Beige"| [[Stress]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Pulmonary''' | |||
|bgcolor="Beige"| [[Sarcoidosis]], [[Severe acute respiratory syndrome]], [[Tuberculosis]], [[Typhoid fever]], | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Renal/Electrolyte''' | |||
|bgcolor="Beige"| [[Spondyloepiphyseal dysplasia -- nephrotic syndrome]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Rheumatology/Immunology/Allergy''' | |||
|bgcolor="Beige"| [[Nezelof syndrome]], [[Sarcoidosis]], [[Systemic lupus erythematosus]], [[Wiskott-aldrich syndrome]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Sexual''' | |||
|bgcolor="Beige"| [[Aids]], [[Hiv-1 disease]], [[Viral hepatitis]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Trauma''' | |||
|bgcolor="Beige"| [[Excessive physical exercise]], [[Stress]] | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Urologic''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|-bgcolor="LightSteelBlue" | |||
| '''Miscellaneous''' | |||
|bgcolor="Beige"| No underlying causes | |||
|- | |||
|} | |||
===Causes in Alphabetical Order=== | |||
{{columns-list| | |||
*[[Aclarubicin]] | |||
*[[Acute viral nasopharyngitis]] | |||
*[[Adenosine deaminase deficiency]] | |||
*[[Aids]] | |||
*[[Alefacept]] | |||
*[[Alemtuzumab]] | |||
*[[Antithymocyte globulin]] | |||
*[[Aplasia cutis congenital]] | |||
*[[Aplastic anemia]] | |||
*[[Ataxia telangiectasia]] | |||
*[[Bendamustine]] | |||
*[[Blinatumomab]] | |||
*[[Cabozantinib]] | |||
*[[Cartilage hair hypoplasia]] | |||
*[[Chemotherapy]] | |||
*[[Chloramphenicol]] | |||
*[[Cladribine]] | |||
*[[Common variable hypogammaglobulinaemia]] | |||
*[[Corticosteroids]] | |||
*[[De vaal syndrome]] | |||
*[[Dimethyl fumarate]] | |||
*[[Dinutuximab]] | |||
*[[Doxorubicin]] | |||
*[[Elotuzumab]] | |||
*[[Epstein-barr virus]] | |||
*[[Eribulin]] | |||
*[[Everolimus]] | |||
*[[Excessive physical exercise]] | |||
*[[Exemestane]] | |||
*[[Fludarabine]] | |||
*[[Hiv-1 disease]] | |||
*[[Hodgkin's disease]] | |||
*[[Human granulocytic ehrlichiosis]] | |||
*[[Human monocytotropic ehrlichiosis]] | |||
*[[Idarubicin]] | |||
*[[Idelalisib]] | |||
*[[Influenza]] | |||
*[[Interferon beta]] | |||
*[[Intestinal lymphangiectasis]] | |||
*[[Ixabepilone]] | |||
*[[Legionella pneumophila]] | |||
*[[Leukemia]] | |||
*[[Linezolid]] | |||
*[[Lorcaserin]] | |||
*[[Lymphangiectasis]] | |||
*[[Malnutrition]] | |||
*[[Mckusick type metaphyseal chondrodysplasia]] | |||
*[[Myelodysplastic syndrome]] | |||
*[[Nezelof syndrome]] | |||
*[[Olaparib]] | |||
*[[Olsalazine]] | |||
*[[Omacetaxine mepesuccinate]] | |||
*[[Oxaliplatin]] | |||
*[[Pamidronate]] | |||
*[[Pancytopenia]] | |||
*[[Pazopanib]] | |||
*[[Pentostatin]] | |||
*[[Purine nucleoside phosphorylase (pnp) deficiency]] | |||
*[[Radiation therapy]] | |||
*[[Reticular dysgenesis]] | |||
*[[Rituximab]] | |||
*[[Sarcoidosis]] | |||
*[[Saxagliptin]] | |||
*[[Schimke immunoosseous dysplasia]] | |||
*[[Severe acute respiratory syndrome]] | |||
*[[Sorafenib]] | |||
*[[Spondyloepiphyseal dysplasia]] | |||
*[[Stress]] | |||
*[[Sunitinib malate]] | |||
*[[Systemic lupus erythematosus]] | |||
*[[Temsirolimus]] | |||
*[[Thrombin human]] | |||
*[[Tuberculosis]] | |||
*[[Typhoid fever]] | |||
*[[Vinblastine]] | |||
*[[Viral hepatitis]] | |||
*[[Waldmann disease]] | |||
*[[Wiskott-aldrich syndrome]] | |||
}} | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: | [[Category:Immunology]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
Latest revision as of 21:52, 10 January 2020
Lymphocytopenia Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.
Overview
Common causes of lymphocytopenia include side effects of drugs that cause platelet changes. Additional common causes include congenital and acquired hematological conditions.
Causes
Common Causes
- Aclarubicin
- Adenosine deaminase deficiency
- Alefacept
- Alemtuzumab
- Antithymocyte globulin
- Aplastic anemia
- Bendamustine
- Blinatumomab
- Cabozantinib
- Chemotherapy
- Chloramphenicol
- Cladribine
- Common variable hypogammaglobulinaemia
- Corticosteroids
- De vaal syndrome
- Dinutuximab
- Doxorubicin
- Elotuzumab
- Eribulin
- Everolimus
- Exemestane
- Fludarabine
- Hodgkin's disease
- Human granulocytic ehrlichiosis
- Human monocytotropic ehrlichiosis
- Idarubicin
- Idelalisib
- Interferon beta
- Ixabepilone
- Legionella pneumophila
- Legionella pneumophila
- Leukemia
- Linezolid
- Lorcaserin
- Lymphangiectasis
- Olaparib
- Olsalazine
- Omacetaxine mepesuccinate
- Oxaliplatin
- Pamidronate
- Pancytopenia
- Pazopanib
- Pentostatin
- Rituximab
- Saxagliptin
- Schimke immunoosseous dysplasia
- Sorafenib
- Sunitinib malate
- Temsirolimus
- Vinblastine
- Waldmann disease
- Wiskott-aldrich syndrome
Causes by Organ System
Causes in Alphabetical Order
- Aclarubicin
- Acute viral nasopharyngitis
- Adenosine deaminase deficiency
- Aids
- Alefacept
- Alemtuzumab
- Antithymocyte globulin
- Aplasia cutis congenital
- Aplastic anemia
- Ataxia telangiectasia
- Bendamustine
- Blinatumomab
- Cabozantinib
- Cartilage hair hypoplasia
- Chemotherapy
- Chloramphenicol
- Cladribine
- Common variable hypogammaglobulinaemia
- Corticosteroids
- De vaal syndrome
- Dimethyl fumarate
- Dinutuximab
- Doxorubicin
- Elotuzumab
- Epstein-barr virus
- Eribulin
- Everolimus
- Excessive physical exercise
- Exemestane
- Fludarabine
- Hiv-1 disease
- Hodgkin's disease
- Human granulocytic ehrlichiosis
- Human monocytotropic ehrlichiosis
- Idarubicin
- Idelalisib
- Influenza
- Interferon beta
- Intestinal lymphangiectasis
- Ixabepilone
- Legionella pneumophila
- Leukemia
- Linezolid
- Lorcaserin
- Lymphangiectasis
- Malnutrition
- Mckusick type metaphyseal chondrodysplasia
- Myelodysplastic syndrome
- Nezelof syndrome
- Olaparib
- Olsalazine
- Omacetaxine mepesuccinate
- Oxaliplatin
- Pamidronate
- Pancytopenia
- Pazopanib
- Pentostatin
- Purine nucleoside phosphorylase (pnp) deficiency
- Radiation therapy
- Reticular dysgenesis
- Rituximab
- Sarcoidosis
- Saxagliptin
- Schimke immunoosseous dysplasia
- Severe acute respiratory syndrome
- Sorafenib
- Spondyloepiphyseal dysplasia
- Stress
- Sunitinib malate
- Systemic lupus erythematosus
- Temsirolimus
- Thrombin human
- Tuberculosis
- Typhoid fever
- Vinblastine
- Viral hepatitis
- Waldmann disease
- Wiskott-aldrich syndrome