Paget-Schroetter disease history and symptoms: Difference between revisions

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{{ Paget-Schroetter disease }}
{{ Paget-Schroetter disease }}


{{CMG}}
{{CMG}} {{Anahita}}


==Overview==
== Overview ==
==History and Symptoms==


A positive history of repetitive [[Upper limb|upper extremity]] movements in a patient presenting with arm discomfort and [[edema]] is suggestive of [[Paget-Schroetter disease]].


The syndrome is also known as “effort-induced thrombosis” as it has been reported to occur after vigorous activity, though it can also occur spontaneously.  
== History and Symptoms ==
* A positive history of vigorous [[Upper limb|upper extremity]] movements or even relatively minor day-to-day arm activities with or without [[dehydration]] in the presence of related symptoms is suggestive of [[Paget-Schroetter disease]].<ref name="pmid21079709">{{cite journal| author=Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK| title=Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis. | journal=West J Emerg Med | year= 2010 | volume= 11 | issue= 4 | pages= 358-62 | pmid=21079709 | doi= | pmc=2967689 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21079709  }}</ref>
* The most common symptoms of [[Paget-Schroetter disease]] include arm discomfort or heaviness, pain, [[Swelling (medical)|swelling]], and [[erythema]] of the upper extremity.


It usually presents in young and otherwise healthy patients, males more often than females.
=== History ===


Symptoms include sudden onset of pain, warmth, redness, and swelling in the arm. These DVT's should be treated as an emergency, but rarely cause fatal pulmonary emboli.  
* Patients with Paget-Schroetter disease or effort thrombosis may have a positive history of:
 
# Sports-related arm exertion (often with sports that require repetitive hyper-[[abduction]], [[extension]] and/or [[external rotation]])
# Minor everyday upper limb activities<ref name="pmid210797092">{{cite journal| author=Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK| title=Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis. | journal=West J Emerg Med | year= 2010 | volume= 11 | issue= 4 | pages= 358-62 | pmid=21079709 | doi= | pmc=2967689 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21079709  }}</ref>
 
* Onset of the [[Paget-Schroetter disease]] is usually [[Acute (medicine)|acute]] or [[Subacute|sub-acute]], nevertheless some cases present with [[Chronic (medical)|chronic]] symptoms.<ref name="pmid210797093">{{cite journal| author=Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK| title=Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis. | journal=West J Emerg Med | year= 2010 | volume= 11 | issue= 4 | pages= 358-62 | pmid=21079709 | doi= | pmc=2967689 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21079709  }}</ref>
* Around 60-80% of cases with [[Paget-Schroetter disease]] have a history of repetitious activity of [[Upper limb|upper extremity]] with 85% occurred within last 24 hours of symptoms onset.<ref name="RinghouseJackson2017">{{cite journal|last1=Ringhouse|first1=Brendan|last2=Jackson|first2=Cody|title=Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study|journal=Military Medicine|volume=182|issue=5|year=2017|pages=e1826–e1829|issn=0026-4075|doi=10.7205/MILMED-D-16-00359}}</ref>
* In 87% of cases, the [[Paget-Schroetter disease]] involves the dominant arm.<ref name="RinghouseJackson20174">{{cite journal|last1=Ringhouse|first1=Brendan|last2=Jackson|first2=Cody|title=Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study|journal=Military Medicine|volume=182|issue=5|year=2017|pages=e1826–e1829|issn=0026-4075|doi=10.7205/MILMED-D-16-00359}}</ref>
 
=== Common Symptoms ===
Common symptoms of [[Paget-Schroetter disease]] include:
 
* Arm discomfort and heaviness
* Pain
* [[Edema]] and [[Swelling (medical)|swelling]]
* [[Erythema]] of the affected [[upper limb]]
* [[Cyanosis]] (usually presented in late stages)<ref name="RinghouseJackson20173">{{cite journal|last1=Ringhouse|first1=Brendan|last2=Jackson|first2=Cody|title=Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study|journal=Military Medicine|volume=182|issue=5|year=2017|pages=e1826–e1829|issn=0026-4075|doi=10.7205/MILMED-D-16-00359}}</ref>
* [[Paresthesia]]<ref name="RinghouseJackson20172">{{cite journal|last1=Ringhouse|first1=Brendan|last2=Jackson|first2=Cody|title=Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study|journal=Military Medicine|volume=182|issue=5|year=2017|pages=e1826–e1829|issn=0026-4075|doi=10.7205/MILMED-D-16-00359}}</ref>
 
=== Less Common Symptoms ===
 
* Occasionally symptoms of [[Paget-Schroetter disease]] can mimic a muscular strain.  
* Patients may initially presented with symptoms of [[Pulmonary embolism|Pulmonary Embolism]].<ref name="HanggeRotellini-Coltvet20172">{{cite journal|last1=Hangge|first1=Patrick|last2=Rotellini-Coltvet|first2=Lisa |last3=Deipolyi|first3=Amy R. |last4=Albadawi|first4=Hassan |last5=Oklu|first5=Rahmi |title=Paget-Schroetter syndrome: treatment of venous thrombosis and outcomes|journal=Cardiovascular Diagnosis and Therapy|volume=7|issue=S3|year=2017|pages=S285–S290|issn=22233652|doi=10.21037/cdt.2017.08.15}}</ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Hematology]]
[[Category:Hematology]]

Latest revision as of 20:16, 23 June 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Anahita Deylamsalehi, M.D.[2]

Overview

A positive history of repetitive upper extremity movements in a patient presenting with arm discomfort and edema is suggestive of Paget-Schroetter disease.

History and Symptoms

History

  • Patients with Paget-Schroetter disease or effort thrombosis may have a positive history of:
  1. Sports-related arm exertion (often with sports that require repetitive hyper-abduction, extension and/or external rotation)
  2. Minor everyday upper limb activities[2]

Common Symptoms

Common symptoms of Paget-Schroetter disease include:

Less Common Symptoms

References

  1. ↑ Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK (2010). "Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis". West J Emerg Med. 11 (4): 358–62. PMC 2967689. PMID 21079709.
  2. ↑ Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK (2010). "Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis". West J Emerg Med. 11 (4): 358–62. PMC 2967689. PMID 21079709.
  3. ↑ Alla VM, Natarajan N, Kaushik M, Warrier R, Nair CK (2010). "Paget-schroetter syndrome: review of pathogenesis and treatment of effort thrombosis". West J Emerg Med. 11 (4): 358–62. PMC 2967689. PMID 21079709.
  4. ↑ Ringhouse, Brendan; Jackson, Cody (2017). "Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study". Military Medicine. 182 (5): e1826–e1829. doi:10.7205/MILMED-D-16-00359. ISSN 0026-4075.
  5. ↑ Ringhouse, Brendan; Jackson, Cody (2017). "Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study". Military Medicine. 182 (5): e1826–e1829. doi:10.7205/MILMED-D-16-00359. ISSN 0026-4075.
  6. ↑ Ringhouse, Brendan; Jackson, Cody (2017). "Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study". Military Medicine. 182 (5): e1826–e1829. doi:10.7205/MILMED-D-16-00359. ISSN 0026-4075.
  7. ↑ Ringhouse, Brendan; Jackson, Cody (2017). "Bringing to Light Symptoms and Treatments of Effort Thrombosis (Paget–Schroetter Syndrome) in the Military Population, a Case Study". Military Medicine. 182 (5): e1826–e1829. doi:10.7205/MILMED-D-16-00359. ISSN 0026-4075.
  8. ↑ Hangge, Patrick; Rotellini-Coltvet, Lisa; Deipolyi, Amy R.; Albadawi, Hassan; Oklu, Rahmi (2017). "Paget-Schroetter syndrome: treatment of venous thrombosis and outcomes". Cardiovascular Diagnosis and Therapy. 7 (S3): S285–S290. doi:10.21037/cdt.2017.08.15. ISSN 2223-3652.

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