Pancoast tumor laboratory tests: Difference between revisions
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{{Pancoast tumor}} | {{Pancoast tumor}} | ||
{{CMG}}; {{AE}} {{Mazia}} | |||
==Overview== | |||
Pancoast tumor is a subtype of [[lung cancer]] located at the [[lung]] [[apex]]. There are no characteristic [[diagnostic]] lab findings associated with Pancoast tumor. The laboratory findings associated with [[lung cancer]] are the following [[neutropenia]], [[hyponatremia]], [[hypokalemia]], [[hypercalcemia]], [[respiratory acidosis]], [[hypercarbia]], [[hypoxia]], and [[tumor]] [[cells]] in [[sputum]] and [[pleural effusion]] [[cytology]]. | |||
==Laboratory tests== | |||
There are no characteristic [[diagnostic]] lab findings associated with Pancoast tumor. The laboratory findings associated with [[lung cancer]] are the following:<ref name="pmid9093348">{{cite journal |vauthors=Muscolino G, Valente M, Andreani S |title=Pancoast tumours: clinical assessment and long-term results of combined radiosurgical treatment |journal=Thorax |volume=52 |issue=3 |pages=284–6 |date=March 1997 |pmid=9093348 |pmc=1758512 |doi= |url=}}</ref><ref name="pmid23702478">{{cite journal |vauthors=Glassman LR, Hyman K |title=Pancoast tumor: a modern perspective on an old problem |journal=Curr Opin Pulm Med |volume=19 |issue=4 |pages=340–3 |date=July 2013 |pmid=23702478 |doi=10.1097/MCP.0b013e3283621b31 |url=}}</ref><ref name="pmid24102007">{{cite journal |vauthors=Foroulis CN, Zarogoulidis P, Darwiche K, Katsikogiannis N, Machairiotis N, Karapantzos I, Tsakiridis K, Huang H, Zarogoulidis K |title=Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment |journal=J Thorac Dis |volume=5 Suppl 4 |issue= |pages=S342–58 |date=September 2013 |pmid=24102007 |pmc=3791502 |doi=10.3978/j.issn.2072-1439.2013.04.08 |url=}}</ref><ref name="pmid10813231">{{cite journal |vauthors=Jones DR, Detterbeck FC |title=Pancoast tumors of the lung |journal=Curr Opin Pulm Med |volume=4 |issue=4 |pages=191–7 |date=July 1998 |pmid=10813231 |doi= |url=}}</ref> | |||
*'''[[Complete blood count]]''' | |||
:*[[Neutropenia]] in [[patients]] with a recent history of [[chemotherapy]] | |||
*'''[[Serum]] [[Electrolyte|electrolytes]]''' | |||
:*[[Hyponatremia]] from [[Syndrome of inappropriate antidiuretic hormone|Syndrome of Inappropriate Antidiuretic Hormone Secretion]] ([[SIADH]]) | |||
:*[[Hypokalemia]] from [[Syndrome of inappropriate antidiuretic hormone|Syndrome of Inappropriate Antidiuretic Hormone Secretion]] ([[SIADH]]) | |||
*[[Hypercalcemia]] with normal [[Parathyroid hormone|PTH levels]] from [[squamous cell carcinoma]] (from [[secretion]] of parathyroid hormone-related peptide (PTH-rP) | |||
*[[Arterial blood gas|'''Arterial blood gas''']] | |||
:*[[Respiratory acidosis]] from [[respiratory failure]] | |||
:*[[Hypercarbia]] from [[respiratory failure]] | |||
:*[[Hypoxia]] from [[respiratory failure]] | |||
*'''[[Sputum]] [[cytology]]''' | |||
:*[[Sputum|Sputum cytology]] demonstrates [[tumor]] [[cells]] | |||
*'''[[Needle]] [[thoracentesis]]''' | |||
:*[[Pleural effusion]] [[cytology]] demonstrates [[tumor]] [[cells]] | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Latest revision as of 14:32, 16 March 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mazia Fatima, MBBS [2]
Overview
Pancoast tumor is a subtype of lung cancer located at the lung apex. There are no characteristic diagnostic lab findings associated with Pancoast tumor. The laboratory findings associated with lung cancer are the following neutropenia, hyponatremia, hypokalemia, hypercalcemia, respiratory acidosis, hypercarbia, hypoxia, and tumor cells in sputum and pleural effusion cytology.
Laboratory tests
There are no characteristic diagnostic lab findings associated with Pancoast tumor. The laboratory findings associated with lung cancer are the following:[1][2][3][4]
- Neutropenia in patients with a recent history of chemotherapy
- Hypercalcemia with normal PTH levels from squamous cell carcinoma (from secretion of parathyroid hormone-related peptide (PTH-rP)
- Arterial blood gas
- Sputum cytology demonstrates tumor cells
- Pleural effusion cytology demonstrates tumor cells
References
- ↑ Muscolino G, Valente M, Andreani S (March 1997). "Pancoast tumours: clinical assessment and long-term results of combined radiosurgical treatment". Thorax. 52 (3): 284–6. PMC 1758512. PMID 9093348.
- ↑ Glassman LR, Hyman K (July 2013). "Pancoast tumor: a modern perspective on an old problem". Curr Opin Pulm Med. 19 (4): 340–3. doi:10.1097/MCP.0b013e3283621b31. PMID 23702478.
- ↑ Foroulis CN, Zarogoulidis P, Darwiche K, Katsikogiannis N, Machairiotis N, Karapantzos I, Tsakiridis K, Huang H, Zarogoulidis K (September 2013). "Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment". J Thorac Dis. 5 Suppl 4: S342–58. doi:10.3978/j.issn.2072-1439.2013.04.08. PMC 3791502. PMID 24102007.
- ↑ Jones DR, Detterbeck FC (July 1998). "Pancoast tumors of the lung". Curr Opin Pulm Med. 4 (4): 191–7. PMID 10813231.