Ankylosing spondylitis risk factors: Difference between revisions
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{{Ankylosing spondylitis}} | {{Ankylosing spondylitis}} | ||
{{CMG}} | {{CMG}} ; {{AE}} {{MKK}} | ||
==Overview== | ==Overview== | ||
There is no known cause specific [[Causes|cause]] for [[ankylosing spondylitis]], though genetic factors seems to play very important role in developing the [[disease]]. In particular, people who are positive for HLA-B27 are at more risk of developing [[ankylosing spondylitis]].[[Ankylosing spondylitis]] is a form of [[chronic]] [[joint]] [[inflammation]] that mostly affects the [[spine]]. Gradually it can cause the bones of the spine to fuse together, a process which is called [[ankylosis]]. | |||
==Risk Factors== | ==Risk Factors== | ||
*There is no known cause specific cause for [[ankylosing spondylitis]], though [[Genetics|genetic]] factors seem to play a very important role in developing the disease. In particular, people who are positive for HLA-B27 are at more risk of developing ankylosing spondylitis.Ankylosing spondylitis is a form of chronic joint [[inflammation]] that mostly affects the [[spine]]. Gradually it can cause the bones of the spine to fuse together, a process which is called [[ankylosis]].<ref name="pmid23841117">{{cite journal |vauthors=Reveille JD, Weisman MH |title=The epidemiology of back pain, axial spondyloarthritis and HLA-B27 in the United States |journal=Am. J. Med. Sci. |volume=345 |issue=6 |pages=431–6 |date=June 2013 |pmid=23841117 |pmc=4122314 |doi= |url=}}</ref> | |||
*The most potent risk factor in the development of [[ankylosing spondylitis]] is positive for [[HLA-B27|HLA-B2]]7. Other risk factors include environmental, gender, and [[age]].<ref name="pmid21358307">{{cite journal |vauthors=Dillon CF, Hirsch R |title=The United States National Health and Nutrition Examination Survey and the epidemiology of ankylosing spondylitis |journal=Am. J. Med. Sci. |volume=341 |issue=4 |pages=281–3 |date=April 2011 |pmid=21358307 |doi=10.1097/MAJ.0b013e31820f8c83 |url=}}</ref> | |||
==References== | ==References== | ||
Latest revision as of 03:09, 30 July 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
There is no known cause specific cause for ankylosing spondylitis, though genetic factors seems to play very important role in developing the disease. In particular, people who are positive for HLA-B27 are at more risk of developing ankylosing spondylitis.Ankylosing spondylitis is a form of chronic joint inflammation that mostly affects the spine. Gradually it can cause the bones of the spine to fuse together, a process which is called ankylosis.
Risk Factors
- There is no known cause specific cause for ankylosing spondylitis, though genetic factors seem to play a very important role in developing the disease. In particular, people who are positive for HLA-B27 are at more risk of developing ankylosing spondylitis.Ankylosing spondylitis is a form of chronic joint inflammation that mostly affects the spine. Gradually it can cause the bones of the spine to fuse together, a process which is called ankylosis.[1]
- The most potent risk factor in the development of ankylosing spondylitis is positive for HLA-B27. Other risk factors include environmental, gender, and age.[2]
References
- ↑ Reveille JD, Weisman MH (June 2013). "The epidemiology of back pain, axial spondyloarthritis and HLA-B27 in the United States". Am. J. Med. Sci. 345 (6): 431–6. PMC 4122314. PMID 23841117.
- ↑ Dillon CF, Hirsch R (April 2011). "The United States National Health and Nutrition Examination Survey and the epidemiology of ankylosing spondylitis". Am. J. Med. Sci. 341 (4): 281–3. doi:10.1097/MAJ.0b013e31820f8c83. PMID 21358307.