Paragonimus infection medical therapy: Difference between revisions
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{{Paragonimus infection}} | {{Paragonimus infection}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
[[Praziquantel]] is the drug of choice to treat paragonimiasis. Bithionol is an alternative drug for treatment of this disease. | [[Praziquantel]] is the drug of choice to treat paragonimiasis. Bithionol is an alternative drug for treatment of this disease. | ||
==Medical Therapy== | |||
[[Praziquantel]] is the drug of choice: adult or pediatric dosage, 25 mg/kg given orally 3 times per day for 2 consecutive days. | |||
Alternatives: [[Triclabendazole]] (not available in the U.S.), adult or pediatric dosage, 10 mg/kg orally once or twice; or [[Bithionol]]: adult or pediatric dosage, 30-50 mg/kg on alternate days for 10-15 doses. | |||
For cerebral disease, a short course of [[corticosteroids]] may be given with the [[praziquantel]] to help reduce the inflammatory response around dying flukes. | |||
===Antimicrobial Regimen=== | |||
:*Preferred regimen (1): [[Praziquantel]] 25 mg/kg PO tid for 3 days<ref>{{Cite web | title =Parasites - Paragonimiasis| url =http://www.cdc.gov/parasites/paragonimus/health_professionals/index.html }}</ref> | |||
:*Preferred regimen (2): [[Triclabendazole]] 10 mg/kg PO qd or bid | |||
:*Alternative regimen (1): [[Bithinol]] 30-50mg/kg PO on alternate days for 10-15 doses | |||
:*Alternative regimen (2): [[Niclosamide]] 2mg/kg PO single dose | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Latest revision as of 18:37, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Praziquantel is the drug of choice to treat paragonimiasis. Bithionol is an alternative drug for treatment of this disease.
Medical Therapy
Praziquantel is the drug of choice: adult or pediatric dosage, 25 mg/kg given orally 3 times per day for 2 consecutive days.
Alternatives: Triclabendazole (not available in the U.S.), adult or pediatric dosage, 10 mg/kg orally once or twice; or Bithionol: adult or pediatric dosage, 30-50 mg/kg on alternate days for 10-15 doses.
For cerebral disease, a short course of corticosteroids may be given with the praziquantel to help reduce the inflammatory response around dying flukes.
Antimicrobial Regimen
- Preferred regimen (1): Praziquantel 25 mg/kg PO tid for 3 days[1]
- Preferred regimen (2): Triclabendazole 10 mg/kg PO qd or bid
- Alternative regimen (1): Bithinol 30-50mg/kg PO on alternate days for 10-15 doses
- Alternative regimen (2): Niclosamide 2mg/kg PO single dose