Beriberi heart disease: Difference between revisions
No edit summary |
m (Bot: Adding CME Category::Cardiology) |
||
| (3 intermediate revisions by one other user not shown) | |||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
'''For patient information, click [[Beriberi (patient information)|here]]''' | '''For patient information, click [[Beriberi (patient information)|here]]''' | ||
'''For the Wikidoc page for Beriberi, click [[Beriberi|here]]''' | |||
{{CMG}} '''Associate Editor-In-Chief:''' {{CZ}} | {{CMG}} '''Associate Editor-In-Chief:''' {{CZ}} | ||
| Line 76: | Line 78: | ||
*[[Dementia|Vascular Dementia]] | *[[Dementia|Vascular Dementia]] | ||
*[[Arthritis|Viral Arthritis]] | *[[Arthritis|Viral Arthritis]] | ||
*[[Wernicke-Korsakoff syndrome]]<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref> <ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref> | *[[Wernicke-Korsakoff syndrome]]<ref>Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016</ref><ref>Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X</ref> | ||
==Diagnosis== | ==Diagnosis== | ||
| Line 122: | Line 124: | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[CME Category::Cardiology]] | |||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
Latest revision as of 04:53, 15 March 2016
For patient information, click here
For the Wikidoc page for Beriberi, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
|
Beriberi Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Beriberi heart disease On the Web |
|
American Roentgen Ray Society Images of Beriberi heart disease |
|
Risk calculators and risk factors for Beriberi heart disease |
Synonyms and keywords: Wet beriberi
Overview
Beriberi heart disease is a form of BeriBeri called wet BeriBeri that involves the heart. It is caused by severe thiamine deficiency.[1]
Epidemiology and Demographics
This disease is most prevalent in the Far East, however, in the past decade its prevalence has markedly decreased.
It occurs mainly in individuals whose staple diet consists of polished rice that is deficient in thiamine but high in carbohydrates.
Diets with a high carbohydrate content require a greater intake of thiamine. White bread enriched with thiamine has helped in this respect.
Because alcohol is high in carbohydrate content but deficient in thiamine, some alcoholics become thiamine deficient and weakness of the heart muscle may occur. The disease is also common in fad diet appliers.[2]
Pathophysiology
Pathologically the heart in cardiac beriberi is most often hypertrophied and dilated, with involvement of both the right and left chambers.
Differential Diagnosis
- Alcoholic Fatty Liver
- Alcoholic Hepatitis
- Alcoholic Ketoacidosis
- Alcoholism
- Anemia
- Anorexia Nervosa
- California Encephalitis
- Campylobacter Infections
- Cardiogenic Shock
- Cardiomyopathy, Alcoholic
- Cardiomyopathy, Cocaine
- Cardiomyopathy, Diabetic Heart Disease
- Cardiomyopathy, Dilated
- Cardiomyopathy, Hypertrophic
- Cardiomyopathy, Peripartum
- Cardiomyopathy, Restrictive
- Cholera
- Cirrhosis
- Delirium
- Delirium Tremens
- Delusional Disorder
- Dementia Due to HIV Disease
- Depression
- Dermatomyositis
- Diabetic Ketoacidosis
- Encephalopathy, Dialysis
- Encephalopathy, Hepatic
- Encephalopathy, Hypertensive
- Encephalopathy, Uremic
- Enterobacter Infections
- Enteroviruses
- Folic Acid Deficiency
- Goiter
- Goiter, Diffuse Toxic
- Hepatic Failure
- Hyperthyroidism
- Ileus
- Irritable Bowel Syndrome
- Metabolic Acidosis
- Myocarditis
- Nerve Entrapment Syndromes
- Polymyositis
- Schizophreniform Disorder
- Scurvy
- Sudden Cardiac Death
- Thyroiditis, Subacute
- Trigeminal Neuralgia
- Vascular Dementia
- Viral Arthritis
- Wernicke-Korsakoff syndrome[3][4]
Diagnosis
History and Symptoms
- The clinical manifestations of beriberi heart disease vary considerably with the severity and rapidity of the onset of the condition.
- Symptoms of heart failure are more frequently seen. Excessive peripheral edema may occur. Dyspnea, weakness, swelling of the ankles, and a nonproductive nocturnal cough are the most common complaints.
- The heart becomes dilated and progresses to heart failure. Beriberi heart disease may cause sudden cardiac dysfunction within days of onset of symptoms. This condition is accompanied by hypotension, tachycardia, and lactic acidosis.[5][6]
- Patients may die within hours or within days of cardiogenic shock and pulmonary edema.
Diagnosis
Laboratory Findings
On laboratory diagnosis for Beriberi heart disease serum pyruvate and lactic acid levels are increased.
Electrocardiogram
The ECG shows low-voltage QRS complex and prolongation of the QT interval.
Chest X-ray
Chest x-ray usually shows congestion of the lungs with pleural effusions.
Treatment
- Treatment including administration of 100 mg of IV thiamine, then 25 mg daily for about 2 weeks causes dramatic improvement.
- Although the initial treatment does not require digoxin and diuretics, a few days after starting thiamine therapy digoxin and diuretics are indicated and produce beneficial results.
- Disturbance of nerves in the legs often accompanies the heart symptoms and thiamine replacement improves this type of polyneuropathy.
Related Chapters
References
- ↑ Givertz, M. M., Colucci, W. S., and Braunwald, E. Clinical aspects of heart failure, high output failure; pulmonary edema. In. Heart Disease, sixth edition. E. Braunwald, D. P. Zipes, P. Libby, and R.O. Bonow, eds. W. B. Saunders, Philadelphia, 2005.
- ↑ Attas M, Hanley HG, Stultz D, Jones MR, McAllister RG. Fulminant beriberi heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms. Circulation, 1978 Vol 58, 566-572 PMID 679449
- ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X
- ↑ Jones RH Jr. Beriberi heart disease. Circulation. 1959 Feb;19 (2): 275-83. PMID 13629790
- ↑ Gelfand D, Bellet S. Cardiovascular manifestations of beriberi based on a study of ten patients. Med Clin North Am. 1949 Nov; 33: 1643-55. PMID 15391541