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==Future or Investigational Therapies== | ==Future or Investigational Therapies== | ||
A 2004 meta-analysis pooling data from three double-blind placebo-controlled studies found the multiple herbal extract Iberogast to be significantly more effective than placebo (p value = 0.001) at treating patients with functional dyspepsia through the targeting of multiple dyspeptic pathologies<ref name="Melzer2004"> {{cite journal|title=Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW-5 (Iberogast)|year=2004|author=Melzer J, Rosch W, Reichling J, Brignoli R, Saller R|journal=Aliment Pharmacol Ther|volume=20|pages=1279–87}}</ref> | A 2004 meta-analysis pooling data from three double-blind placebo-controlled studies found the multiple herbal extract Iberogast to be significantly more effective than placebo (p value = 0.001) at treating patients with functional dyspepsia through the targeting of multiple dyspeptic pathologies.<ref name="Melzer2004"> {{cite journal|title=Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW-5 (Iberogast)|year=2004|author=Melzer J, Rosch W, Reichling J, Brignoli R, Saller R|journal=Aliment Pharmacol Ther|volume=20|pages=1279–87}}</ref> This German-made phytopharmaceutical was found to be equivalent to cisapride and significantly superior to metochlopramide at reducing the symptoms of functional dyspepsia over a four week period.<ref name="Rosch2002">{{cite journal|journal=Z Gastroenterol|title=A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepsia|author=Rosch w, Vinson B, Sassin, I|year=2002|volume=40|pages=401–8}}</ref><ref name="Hanisch2005">{{cite journal|journal=Med Klinik|title=The efficacy and safety of STW 5 versus Metochlopramide oral for functional dyspepsia under practice conditions (in German)|author=Hanisch J, Bock P, Vinson B|year=2005|volume=100|pages107}}</ref> Retrospective surveillance of 40,961 children (12 years and under) found no serious side-effects.<ref name="Leichtle1999">{{cite journal|journal=Forschungsbericht Steigerwald Arzneimittelwerk|title=Experience reports on the use of Iberogast in children (in German)|author=Liechtle K|year=1999|volume=GmbH}}</ref> | ||
==References== | ==References== | ||
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{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Digestive disease symptoms]] | [[Category:Digestive disease symptoms]] | ||
Latest revision as of 21:29, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Future or Investigational Therapies
A 2004 meta-analysis pooling data from three double-blind placebo-controlled studies found the multiple herbal extract Iberogast to be significantly more effective than placebo (p value = 0.001) at treating patients with functional dyspepsia through the targeting of multiple dyspeptic pathologies.[1] This German-made phytopharmaceutical was found to be equivalent to cisapride and significantly superior to metochlopramide at reducing the symptoms of functional dyspepsia over a four week period.[2][3] Retrospective surveillance of 40,961 children (12 years and under) found no serious side-effects.[4]
References
- ↑ Melzer J, Rosch W, Reichling J, Brignoli R, Saller R (2004). "Meta-analysis: phytotherapy of functional dyspepsia with the herbal drug preparation STW-5 (Iberogast)". Aliment Pharmacol Ther. 20: 1279&ndash, 87.
- ↑ Rosch w, Vinson B, Sassin, I (2002). "A randomised clinical trial comparing the efficacy of a herbal preparation STW 5 with the prokinetic drug cisapride in patients with dysmotility type of functional dyspepsia". Z Gastroenterol. 40: 401&ndash, 8.
- ↑ Hanisch J, Bock P, Vinson B (2005). "The efficacy and safety of STW 5 versus Metochlopramide oral for functional dyspepsia under practice conditions (in German)". Med Klinik. 100. Text "pages107" ignored (help)
- ↑ Liechtle K (1999). "Experience reports on the use of Iberogast in children (in German)". Forschungsbericht Steigerwald Arzneimittelwerk. GmbH.