Heartburn causes: Difference between revisions

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Latest revision as of 15:10, 28 September 2020

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: José Eduardo Riceto Loyola Junior, M.D.[2]

Overview

Heartburn is commonly caused by gastroesophageal reflux disease (GERD) or adverse reactions to various food and drugs, causing esophagitis. Life threatening causes of heartburn are far less common and include acute coronary syndromes and esophageal cancer.

Causes

Life Threatening Causes

These causes present with chest pain that may present similarly to heartburn and also other clinical features that occur with heartburn:

Common Causes

Gastroesophageal reflux disease (GERD)^[1]
Esophagitis ^[2]
Hiatal hernia^[3]
Motility disorders (e.g., gastroparesis)
Peptic ulcer disorder
Lifestyle:
- Exercise
- Obesity
- Smoking (tobacco)
- Stress
- Supine body position
- tight-fitting clothing
Medications:
- Alpha-adrenergic antagonists
- Anticholinergic agents
- Aspirin and other nonsteroidal anti-inflammatory drugs
- Beta2 -adrenergic drugs
- Barbiturates
- Benzodiazepines
- Bisphosphonates
- Calcium channel blockers
- Chemotherapy
- Dopamine
- Estrogen
- Iron
- Narcotic analgesics
- Nitrates
- Potassium
- Progesterone
- Prostaglandins
- Quinidine
- Tetracycline
- Theophylline
- Tricyclic antidepressants
- Zidovudine
Dietary:
- Alcohol
- Caffeinated beverages
- Carbonated beverages
- Chocolate
- Citrus fruit or juices
- Fatty foods
- Garlic or onions
- Mint (peppermint, spearmint)
- Salt and salt substitutes
- Spicy foods
- Tomatoes/tomato juice
Other:
- Genetics
- Pregnancy^[4]

Less Common Causes

References

↑ De Giorgi F, Palmiero M, Esposito I, Mosca F, Cuomo R (October 2006). "Pathophysiology of gastro-oesophageal reflux disease". Acta Otorhinolaryngol Ital. 26 (5): 241–6. PMC 2639970. PMID 17345925.
↑ Fennerty MB, Johnson DA (April 2006). "Heartburn severity does not predict disease severity in patients with erosive esophagitis". MedGenMed. 8 (2): 6. PMC 1785158. PMID 16926745.
↑ Karamanolis G, Polymeros D, Triantafyllou K, Adamopoulos A, Barbatzas C, Vafiadis I, Ladas SD (June 2013). "Hiatal hernia predisposes to nocturnal gastro-oesophageal reflux". United European Gastroenterol J. 1 (3): 169–74. doi:10.1177/2050640613490295. PMC 4040758. PMID 24917956.
↑ "www.worldgastroenterology.org" (PDF).

[pmid17345925-1] De Giorgi F, Palmiero M, Esposito I, Mosca F, Cuomo R (October 2006). "Pathophysiology of gastro-oesophageal reflux disease". Acta Otorhinolaryngol Ital. 26 (5): 241–6. PMC 2639970. PMID 17345925.

[pmid16926745-2] Fennerty MB, Johnson DA (April 2006). "Heartburn severity does not predict disease severity in patients with erosive esophagitis". MedGenMed. 8 (2): 6. PMC 1785158. PMID 16926745.

[pmid24917956-3] Karamanolis G, Polymeros D, Triantafyllou K, Adamopoulos A, Barbatzas C, Vafiadis I, Ladas SD (June 2013). "Hiatal hernia predisposes to nocturnal gastro-oesophageal reflux". United European Gastroenterol J. 1 (3): 169–74. doi:10.1177/2050640613490295. PMC 4040758. PMID 24917956.

[urlwww.worldgastroenterology.org-4] "www.worldgastroenterology.org" (PDF).

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[2]

[3]

[4]

@@ Line 1: / Line 1: @@
 __NOTOC__
 {{Heartburn}}
-Please help WikiDoc by adding content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.
+{{CMG}} {{AE}} {{Jose}}
+==Overview==
+[[Heartburn]] is commonly caused by [[gastroesophageal reflux disease]] ([[GERD]]) or adverse reactions to various food and drugs, causing [[esophagitis]].
+Life threatening causes of [[heartburn]] are far less common and include [[acute coronary syndromes]] and [[esophageal cancer]].
+==Causes==
+===Life Threatening Causes===
+These causes present with [[chest pain]] that may present similarly to [[heartburn]] and also other clinical features that occur with [[heartburn]]:
+*[[Acute coronary syndrome]]
+*[[Esophageal cancer]]
+*[[Mediastinitis]]
+===Common Causes===
+*[[Gastroesophageal reflux disease]] ([[GERD]])<ref name="pmid17345925">{{cite journal |vauthors=De Giorgi F, Palmiero M, Esposito I, Mosca F, Cuomo R |title=Pathophysiology of gastro-oesophageal reflux disease |journal=Acta Otorhinolaryngol Ital |volume=26 |issue=5 |pages=241–6 |date=October 2006 |pmid=17345925 |pmc=2639970 |doi= |url=}}</ref>
+*[[Esophagitis]] <ref name="pmid16926745">{{cite journal |vauthors=Fennerty MB, Johnson DA |title=Heartburn severity does not predict disease severity in patients with erosive esophagitis |journal=MedGenMed |volume=8 |issue=2 |pages=6 |date=April 2006 |pmid=16926745 |pmc=1785158 |doi= |url=}}</ref>
+*[[Hiatal hernia]]<ref name="pmid24917956">{{cite journal |vauthors=Karamanolis G, Polymeros D, Triantafyllou K, Adamopoulos A, Barbatzas C, Vafiadis I, Ladas SD |title=Hiatal hernia predisposes to nocturnal gastro-oesophageal reflux |journal=United European Gastroenterol J |volume=1 |issue=3 |pages=169–74 |date=June 2013 |pmid=24917956 |pmc=4040758 |doi=10.1177/2050640613490295 |url=}}</ref>
+*Motility disorders (e.g., [[gastroparesis]])
+*[[Peptic ulcer]] disorder
+*Lifestyle:
+**Exercise
+**Obesity
+**[[Smoking]] (tobacco)
+**[[Stress]]
+**Supine body position
+**tight-fitting clothing
+*Medications:
+**[[Alpha-adrenergic antagonist]]s
+**[[Anticholinergic]] agents
+**[[Aspirin]] and other [[nonsteroidal anti-inflammatory drugs]]
+**[[Beta2 -adrenergic drugs]]
+**[[Barbiturates]]
+**[[Benzodiazepines]]
+**[[Bisphosphonates]]
+**[[Calcium channel blockers]]
+**[[Chemotherapy]]
+**[[Dopamine]]
+**[[Estrogen]]
+**[[Iron]]
+**[[Narcotic analgesics]]
+**[[Nitrates]]
+**[[Potassium]]
+**[[Progesterone]]
+**[[Prostaglandins]]
+**[[Quinidine]]
+**[[Tetracycline]]
+**[[Theophylline]]
+**[[Tricyclic antidepressants]]
+**[[Zidovudine]]
+*Dietary:
+**[[Alcohol]]
+**Caffeinated beverages
+**Carbonated beverages
+**Chocolate
+**Citrus fruit or juices
+**Fatty foods
+**Garlic or onions
+**Mint (peppermint, spearmint)
+**Salt and salt substitutes
+**Spicy foods
+**Tomatoes/tomato juice
+*Other:
+**Genetics
+**Pregnancy<ref name="urlwww.worldgastroenterology.org">{{cite web |url=https://www.worldgastroenterology.org/UserFiles/file/WDHD-2015-handbook-final.pdf |title=www.worldgastroenterology.org |format= |work= |accessdate=}}</ref>
+==Less Common Causes==
+*[[Scleroderma]]
+*[[Zollinger-Ellison syndrome]]
+*[[Pericarditis]]
 ==References==
-{{reflist|2}}
+{{Reflist|2}}
-{{WH}}
-{{WS}}
+[[Category:General practice]]
-[[Category:Needs content]]
+[[Category:Gastroenterology]]
-[[Category:Disease]]
+[[Category:Digestive disease symptoms]]
-[[Category:Bacterial diseases]]
+[[Category:Up-To-Date]]
-[[Category:Pulmonology]]
-[[Category:Infectious disease]]