Primary biliary cirrhosis other diagnostic studies: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Primary biliary cirrhosis}} | {{Primary biliary cirrhosis}} | ||
{{CMG}}; {{AE}} {{SH}} | |||
==Overview== | |||
Other diagnostic studies for primary biliary cirrhosis include [[liver biopsy]], which demonstrates [[inflammation]] of the [[Bile duct|bile ducts]],characterized by [[Intraepithelial lymphocyte|intraepithelial lymphocytes]] and periductal [[epithelioid]] [[Granuloma|granulomata]]. | |||
==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
===Liver Biopsy=== | ===Liver Biopsy=== | ||
Primary biliary cirrhosis is characterized by interlobular bile duct destruction. | Primary biliary cirrhosis is characterized by interlobular bile duct destruction. [[Histopathologic]] findings of primary biliary cirrhosis include:<ref name="pmid10976014">{{cite journal | pmid = 10976014 | doi=10.1053/bega.2000.0103 | volume=14 | issue=4 | title=Destruction of bile ducts in primary biliary cirrhosis | year=2000 | month=August | author=Nakanuma Y, Tsuneyama K, Sasaki M, Harada K | journal=Baillieres Best Pract Res Clin Gastroenterol | pages=549–70}}</ref> | ||
*Inflammation of the bile ducts, characterized by intraepithelial [[lymphocyte]]s | *Inflammation of the bile ducts, characterized by intraepithelial [[lymphocyte]]s | ||
*Periductal [[epithelioid]] [[granulomata]] | *Periductal [[epithelioid]] [[Granuloma|granulomata]]. | ||
A liver biopsy is necessary to determine the stage of disease. | A liver biopsy is necessary to determine the stage of disease. | ||
===ERCP=== | ===ERCP=== | ||
Abdominal [[medical ultrasonography|ultrasound]] or a [[CT scan]] is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a [[liver biopsy]], and | Abdominal [[medical ultrasonography|ultrasound]] or a [[CT scan]] is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a [[liver biopsy]], and if uncertainty remained [[endoscopic retrograde cholangiopancreatography]] (ERCP, an [[endoscopy|endoscopic]] investigation of the [[bile duct]]). | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
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[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Hepatology]] | [[Category:Hepatology]] | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Rheumatology]] | |||
[[Category: | [[Category:Medicine]] | ||
[[Category:Up-To-Date]] | |||
Latest revision as of 23:49, 29 July 2020
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Primary Biliary Cirrhosis Microchapters |
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Differentiating Primary Biliary Cirrhosis from other Diseases |
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Diagnosis |
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Treatment |
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Primary biliary cirrhosis other diagnostic studies On the Web |
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Risk calculators and risk factors for Primary biliary cirrhosis other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
Other diagnostic studies for primary biliary cirrhosis include liver biopsy, which demonstrates inflammation of the bile ducts,characterized by intraepithelial lymphocytes and periductal epithelioid granulomata.
Other Diagnostic Studies
Liver Biopsy
Primary biliary cirrhosis is characterized by interlobular bile duct destruction. Histopathologic findings of primary biliary cirrhosis include:[1]
- Inflammation of the bile ducts, characterized by intraepithelial lymphocytes
- Periductal epithelioid granulomata.
A liver biopsy is necessary to determine the stage of disease.
ERCP
Abdominal ultrasound or a CT scan is usually performed to rule out blockage to the bile ducts. Previously most suspected sufferers underwent a liver biopsy, and if uncertainty remained endoscopic retrograde cholangiopancreatography (ERCP, an endoscopic investigation of the bile duct).