Kidney stone laboratory findings: Difference between revisions
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{{Kidney stone}} | {{Kidney stone}} | ||
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==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of nephrolithiasis include [[hypercalcemia]], [[hypercalciuria]], [[hyperoxaluria]], [[hypocitraturia]], [[hyperuricemia]] and [[hyperuricosuria]] | |||
==Laboratory Findings== | ==Laboratory Findings== | ||
* | *Laboratory findings consistent with the diagnosis of nephrolithiasis include: | ||
**[[ | **[[Hypercalcemia]] | ||
**[[ | **[[Hypercalciuria]] | ||
**[[ | **[[Hyperoxaluria]] | ||
**[[ | **[[Hypocitraturia]] | ||
** | **[[Hyperuricemia]] | ||
* | **[[Hyperuricosuria]] | ||
The urine calcium/creatinine ratio should be less than 0.14<ref name="Foley Boccuzzi 2010 pp. 683–686">{{cite journal | last=Foley | first=Kevin F. | last2=Boccuzzi | first2=Lorenzo | title=Urine Calcium: Laboratory Measurement and Clinical Utility | journal=Laboratory Medicine | volume=41 | issue=11 | date=2010 | issn=0007-5027 | doi=10.1309/LM9SO94ZNBHEDNTM | pages=683–686}}</ref>. Higher values suggest hypercalcuria. | |||
The urine calcium to urinary citrate ratio (UCa/Ucit) is not well studied, but should maybe be < 0.7<ref name="pmid29878514">{{cite journal| author=Gafni RI, Langman CB, Guthrie LC, Brillante BA, James R, Yovetich NA | display-authors=etal| title=Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity. | journal=J Bone Miner Res | year= 2018 | volume= 33 | issue= 10 | pages= 1741-1747 | pmid=29878514 | doi=10.1002/jbmr.3480 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29878514 }} </ref> Higher values may suggest hyperparathyroidism. | |||
==References== | ==References== | ||
{{ | {{Reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category: (name of the system)]] | |||
Latest revision as of 18:28, 6 March 2024
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]
Overview
Laboratory findings consistent with the diagnosis of nephrolithiasis include hypercalcemia, hypercalciuria, hyperoxaluria, hypocitraturia, hyperuricemia and hyperuricosuria
Laboratory Findings
- Laboratory findings consistent with the diagnosis of nephrolithiasis include:
The urine calcium/creatinine ratio should be less than 0.14[1]. Higher values suggest hypercalcuria.
The urine calcium to urinary citrate ratio (UCa/Ucit) is not well studied, but should maybe be < 0.7[2] Higher values may suggest hyperparathyroidism.
References
- ↑ Foley, Kevin F.; Boccuzzi, Lorenzo (2010). "Urine Calcium: Laboratory Measurement and Clinical Utility". Laboratory Medicine. 41 (11): 683–686. doi:10.1309/LM9SO94ZNBHEDNTM. ISSN 0007-5027.
- ↑ Gafni RI, Langman CB, Guthrie LC, Brillante BA, James R, Yovetich NA; et al. (2018). "Hypocitraturia Is an Untoward Side Effect of Synthetic Human Parathyroid Hormone (hPTH) 1-34 Therapy in Hypoparathyroidism That May Increase Renal Morbidity". J Bone Miner Res. 33 (10): 1741–1747. doi:10.1002/jbmr.3480. PMID 29878514.