Carbenicillin indanyl sodium: Difference between revisions
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==Overview== | ==Overview== | ||
'''Carindacillin''' ([[International Nonproprietary Name|INN]]), also known as '''Carbenicillin indanyl''' ([[United States Adopted Name|USAN]]) is a [[penicillins|penicillin]] [[antibiotic]]. It is a [[prodrug]] of [[carbenicillin]].<ref name="pmid4558137">{{cite journal |author=English AR, Retsema JA, Ray VA, Lynch JE |title=Carbenicillin indanyl sodium, an orally active derivative of carbenicillin |journal=Antimicrob. Agents Chemother. |volume=1 |issue=3 |pages=185–91 |year=1972 |month=March |pmid=4558137 |pmc=444190 |doi= |url=http://aac.asm.org/cgi/pmidlookup?view=long&pmid=4558137}}</ref> | |||
==Category== | ==Category== | ||
[[penicillins|penicillin]] [[antibiotic]] | |||
==US Brand Names== | ==US Brand Names== | ||
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==FDA Package Insert== | ==FDA Package Insert== | ||
'''[[Carbenicillin indanyl sodium description|Description]]''' | '''[[Carbenicillin indanyl sodium description|Description]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium clinical pharmacology|Clinical Pharmacology]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium microbiology|Microbiology]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium indications and usage|Indications and Usage]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium contraindications|Contraindications]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium warnings and precautions|Warnings and Precautions]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium adverse reactions|Adverse Reactions]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium overdosage|Overdosage]]''' | ||
'''| [[Carbenicillin | '''| [[Carbenicillin indanyl sodium dosage and administration|Dosage and Administration]]''' | ||
'''| [[Carbenicillin indanyl sodium how supplied|How Supplied]]''' | |||
'''| [[Carbenicillin | |||
==Mechanism of Action== | ==Mechanism of Action== | ||
Latest revision as of 04:22, 2 January 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamed Moubarak, M.D. [2]
Overview
Carindacillin (INN), also known as Carbenicillin indanyl (USAN) is a penicillin antibiotic. It is a prodrug of carbenicillin.[1]
Category
US Brand Names
GEOCILLIN®
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Overdosage | Dosage and Administration | How Supplied
Mechanism of Action
Carbenicillin exerts its antibacterial activity by interference with final cell wall synthesis of susceptible bacteria. The antibacterial activity of Geocillin is due to its rapid conversion to carbenicillin by hydrolysis after absorption. Though Geocillin provides substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal activity.[2]
References
- ↑ English AR, Retsema JA, Ray VA, Lynch JE (1972). "Carbenicillin indanyl sodium, an orally active derivative of carbenicillin". Antimicrob. Agents Chemother. 1 (3): 185–91. PMC 444190. PMID 4558137. Unknown parameter
|month=ignored (help) - ↑ "GEOCILLIN (CARBENICILLIN INDANYL SODIUM) TABLET, FILM COATED [ROERIG]". Text " accessdate" ignored (help)