Stavudine adverse reactions: Difference between revisions

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==Adverse Reactions==


The following adverse reactions are discussed in greater detail in other sections of the labeling:


<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) POWDER, FOR SOLUTION [E.R. SQUIBB & SONS, L.L.C.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7745cad8-720d-4755-87c7-9147c0915b0f | publisher =  | date =  | accessdate =  }}</ref>
*:[[Lactic acidosis]] and severe [[hepatomegaly]] with steatosis
 
*:Hepatic injury
 
*:Neurologic symptoms and motor weakness
 
*:[[Pancreatitis]]
 
*:[[lipoatrophy]]/[[lipodystrophy]]
 
When ZERIT is used in combination with other agents with similar toxicities, the incidence of adverse reactions may be higher than when stavudine is used alone.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) POWDER, FOR SOLUTION [E.R. SQUIBB & SONS, L.L.C.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7745cad8-720d-4755-87c7-9147c0915b0f | publisher =  | date =  | accessdate =  }}</ref>


==References==
==References==

Latest revision as of 07:14, 3 January 2014

Stavudine
Zerit® FDA Package Insert
Description
Clinical Pharmacology
Microbiology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Clinical Studies
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]

Adverse Reactions

The following adverse reactions are discussed in greater detail in other sections of the labeling:

  • Hepatic injury
  • Neurologic symptoms and motor weakness

When ZERIT is used in combination with other agents with similar toxicities, the incidence of adverse reactions may be higher than when stavudine is used alone.[1]

References

  1. "ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) CAPSULE, GELATIN COATED ZERIT (STAVUDINE) POWDER, FOR SOLUTION [E.R. SQUIBB & SONS, L.L.C.]".

Adapted from the FDA Package Insert.