Esophageal cancer classification: Difference between revisions

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{{Esophageal cancer}}
{{Esophageal cancer}}
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==Overview==
==Overview==
Esophageal cancer may be classified into [[squamous cell carcinoma]] or [[adenocarcinoma]] based on [[histology]].
==Classification==
==Classification==
Esophageal cancers are typically [[carcinoma]]s, which arise from the [[epithelium]], or surface lining of the esophagus. Most esophageal cancer fall into one of two classes: [[squamous cell carcinoma]]s, which are similar to [[head and neck cancer]] in their appearance and association with [[tobacco]] and [[alcohol]] consumption, and [[adenocarcinoma]]s, which are often associated with a history of [[gastroesophageal reflux disease]] and [[Barrett's esophagus]].The adenocarcinomas of esophagus present clinically as that of gastric adenocarcinomas and make up more than 70% of esophageal cancers.<ref name="pmid14657432">{{cite journal| author=Enzinger PC, Mayer RJ| title=Esophageal cancer. | journal=N Engl J Med | year= 2003 | volume= 349 | issue= 23 | pages= 2241-52 | pmid=14657432 | doi=10.1056/NEJMra035010 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14657432  }} </ref>
Esophageal cancers are typically [[carcinoma]]s, which arise from the [[epithelium]], or surface lining of the esophagus. Most esophageal cancers fall into one of two classes according to their histology.
<ref name="pmid23207041">{{cite journal |vauthors=Buas MF, Vaughan TL |title=Epidemiology and risk factors for gastroesophageal junction tumors: understanding the rising incidence of this disease |journal=Semin Radiat Oncol |volume=23 |issue=1 |pages=3–9 |year=2013 |pmid=23207041 |pmc=3535292 |doi=10.1016/j.semradonc.2012.09.008 |url=}}</ref>
 
*'''[[Squamous cell carcinoma]]'''
**Esophageal squamous cell carcinoma are similar to [[head and neck cancer]] in their appearance and are associated with [[smoking]] and [[alcohol]] consumption.
*'''[[Adenocarcinoma]]'''
**Esophageal adenocarcinomas make up more than 70% of esophageal cancers.
**They are often associated with a history of [[gastroesophageal reflux disease]] and [[Barrett's esophagus]].
 
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[[Image:Ac.jpg|thumb|center|300px|Esophageal adenocarcinoma by Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=12475495]]
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[[Image:ssc.jpg|thumb|center|500px|Esophageal squamous cell carcinoma by Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=31284085]]
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==References==
==References==
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[[Category:Disease]]
[[Category:Disease]]
[[Category:Types of cancer]]
[[Category:Types of cancer]]
[[Category:Gastroenterology]]
[[Category:Gastroenterology]]
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Latest revision as of 19:46, 3 January 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

Esophageal cancer may be classified into squamous cell carcinoma or adenocarcinoma based on histology.

Classification

Esophageal cancers are typically carcinomas, which arise from the epithelium, or surface lining of the esophagus. Most esophageal cancers fall into one of two classes according to their histology. [1]

Esophageal adenocarcinoma by Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=12475495
Esophageal squamous cell carcinoma by Nephron - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=31284085

References

  1. Buas MF, Vaughan TL (2013). "Epidemiology and risk factors for gastroesophageal junction tumors: understanding the rising incidence of this disease". Semin Radiat Oncol. 23 (1): 3–9. doi:10.1016/j.semradonc.2012.09.008. PMC 3535292. PMID 23207041.


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