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{{Laryngeal cancer}}
{{Laryngeal cancer}}
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==Overview==
==Overview==
In the United States, the age-adjusted [[prevalence]] of laryngeal cancer is 19.5 per 100,000 in 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>  The age-adjusted incidence of laryngeal cancer in the United States between 2007 and 2011 is 3.3 per 100,000.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>  The estimated number of new cases in the United States in 2014 is 12,630, which correspond to 0.8% of all new cancer cases.<ref name=cancer.gov>[http://seer.cancer.gov/statfacts/html/laryn.html cancer.gov]</ref>  Laryngeal cancer is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH), which means that laryngeal cancer affects less than 200,000 people in the US population.<ref name=NIH>{{cite web | title =Annual Report on the Rare Diseases and Conditions Research| url=http://rarediseases.info.nih.gov/ | publsiher=National Institutes of Health | accessdate=2007-03-22}}</ref>  In the United Kingdom, 2,369 people were diagnosed with laryngeal cancer in 2011.<ref name=UK>[http://www.cancerresearchuk.org/cancer-info/cancerstats/types/larynx/ Cancer research UK]</ref>
The [[prevalence]] of [[laryngeal cancer]] is approximately 19.5 per 100,000 individuals in the United States. The [[incidence]] of laryngeal cancer is approximately 3.3 per 100,000 individuals in the United States. The estimated number of new cases in the United States in 2014 is 12,630 which corresponds to 0.8% of all new [[cancer]] cases. [[Laryngeal cancer]] is listed as a "[[rare disease]]" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH), which means that [[laryngeal cancer]] affects less than 200,000 people in the US [[population]]. In the United Kingdom, 2,369 people were diagnosed with [[laryngeal cancer]] in 2011.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
===Prevalence===
===Prevalence===
 
*The [[prevalence]] of [[laryngeal cancer]] is approximately 19.5 per 100,000 individuals in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref><ref name="pmid21654320">{{cite journal |vauthors=Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R |title=Epidemiology of cancer from the oral cavity and oropharynx |journal=Eur J Gastroenterol Hepatol |volume=23 |issue=8 |pages=633–41 |date=August 2011 |pmid=21654320 |doi=10.1097/MEG.0b013e3283484795 |url=}}</ref><ref name="pmid28055103">{{cite journal |vauthors=Siegel RL, Miller KD, Jemal A |title=Cancer Statistics, 2017 |journal=CA Cancer J Clin |volume=67 |issue=1 |pages=7–30 |date=January 2017 |pmid=28055103 |doi=10.3322/caac.21387 |url=}}</ref>
* In the United States, the age-adjusted [[prevalence]] of laryngeal cancer is 19.5 per 100,000 in 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
===Incidence===
===Incidence===
 
*The [[incidence]] of [[laryngeal cancer]] is approximately 3.3 per 100,000 individuals in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref><ref name="pmid21654320">{{cite journal |vauthors=Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R |title=Epidemiology of cancer from the oral cavity and oropharynx |journal=Eur J Gastroenterol Hepatol |volume=23 |issue=8 |pages=633–41 |date=August 2011 |pmid=21654320 |doi=10.1097/MEG.0b013e3283484795 |url=}}</ref><ref name="pmid22752881">{{cite journal |vauthors=Bray F, Ren JS, Masuyer E, Ferlay J |title=Global estimates of cancer prevalence for 27 sites in the adult population in 2008 |journal=Int. J. Cancer |volume=132 |issue=5 |pages=1133–45 |date=March 2013 |pmid=22752881 |doi=10.1002/ijc.27711 |url=}}</ref>
* The delay-adjusted [[incidence]] of laryngeal cancer in 2011 was estimated to be 2.98 per 100,000 persons in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
*In the United Kingdom, 2,369 people were diagnosed with [[laryngeal cancer]] in 2011.<ref name="UK">[http://www.cancerresearchuk.org/cancer-info/cancerstats/types/larynx/ Cancer research UK]</ref><ref name="pmid28055103">{{cite journal |vauthors=Siegel RL, Miller KD, Jemal A |title=Cancer Statistics, 2017 |journal=CA Cancer J Clin |volume=67 |issue=1 |pages=7–30 |date=January 2017 |pmid=28055103 |doi=10.3322/caac.21387 |url=}}</ref>
 
* In 2011, the age-adjusted [[incidence]] of laryngeal cancer was 2.93 per 100,000 persons in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
 
* In the United Kingdom, 2,369 people were diagnosed with laryngeal cancer.<ref name=UK>[http://www.cancerresearchuk.org/cancer-info/cancerstats/types/larynx/ Cancer research UK]</ref>
===Age===
===Age===
 
* While the overall age-adjusted [[incidence]] of [[laryngeal cancer]] in the United States between 2007 and 2011 is 3.3 per 100,000, the age-adjusted [[incidence]] of [[laryngeal cancer]] by age category is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref><ref name="pmid22752881">{{cite journal |vauthors=Bray F, Ren JS, Masuyer E, Ferlay J |title=Global estimates of cancer prevalence for 27 sites in the adult population in 2008 |journal=Int. J. Cancer |volume=132 |issue=5 |pages=1133–45 |date=March 2013 |pmid=22752881 |doi=10.1002/ijc.27711 |url=}}</ref>
* While the overall age-adjusted [[incidence]] of laryngeal cancer in the United States between 2007 and 2011 is 3.3 per 100,000, the age-adjusted [[incidence]] of laryngeal cancer by age category is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** Under 65 years: 1.6 per 100,000
** Under 65 years: 1.6 per 100,000
** 65 and over: 1.48 per 100,000
** 65 and over: 1.48 per 100,000
 
===Genetics===
Loss of chromosomes 3p, 5q, 8p, 9p, 18q and 21q have been reported in laryngeal cancer<ref name="pmid26940775">{{cite journal |vauthors=de Miguel-Luken MJ, Chaves-Conde M, Carnero A |title=A genetic view of laryngeal cancer heterogeneity |journal=Cell Cycle |volume=15 |issue=9 |pages=1202–12 |date=May 2016 |pmid=26940775 |doi=10.1080/15384101.2016.1156275 |url=}}</ref>
===Gender===
===Gender===
 
* In the United States, the age-adjusted [[prevalence]] of [[laryngeal cancer]] by gender in 2011 was:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* In the United States, the age-adjusted [[prevalence]] of laryngeal cancer by gender in 2011 is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** In males: 35.8 per 100,000
** In males: 35.8 per 100,000
** In females: 6.6 per 100,000
** In females: 6.6 per 100,000
 
* In the United States, the delay-adjusted [[incidence]] of [[laryngeal cancer]] by gender in 2011 was:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* In the United States, the delay-adjusted [[incidence]] of laryngeal cancer by gender in 2011 is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** In males: 5.28 per 100,000 persons
** In males: 5.28 per 100,000 persons
** In females: 1.1 per 100,000 persons
** In females: 1.1 per 100,000 persons
 
* In the United States, the age-adjusted [[incidence]] of laryngeal cancer by gender on 2011 was:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* In the United States, the age-adjusted [[incidence]] of laryngeal cancer by gender on 2011 is:<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
** In males: 5.18 per 100,000 persons
** In males: 5.18 per 100,000 persons
** In females: 1.08 per 100,000 persons
** In females: 1.08 per 100,000 persons
 
* Shown below is an image depicting the delay-adjusted [[incidence]] and observed [[incidence]] of [[laryngeal cancer]] by gender and [[race]] in the United States between 1975 and 2011.  These graphs are adapted from [[SEER]]: The Surveillance, [[Epidemiology]], and End Results Program of the National Cancer Institute.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* Shown below is an image depicting the delay-adjusted [[incidence]] and observed [[incidence]] of laryngeal cancer by gender and race in the United States between 1975 and 2011.  These graphs are adapted from [[SEER]]: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>


[[Image:Incidence of laryngeal cancer by age and race in USA.PNG|Delay-adjusted [[incidence]] and observed [[incidence]] of laryngeal cancer by gender and race in the United States between 1975 and 2011]]
[[Image:Incidence of laryngeal cancer by age and race in USA.PNG|Delay-adjusted [[incidence]] and observed [[incidence]] of laryngeal cancer by gender and race in the United States between 1975 and 2011]]


===Race===
===Race===
 
* Shown below is a table depicting the age-adjusted [[prevalence]] of [[laryngeal cancer]] by race in 2011 in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref><ref name="pmid19641042">{{cite journal |vauthors=Settle K, Posner MR, Schumaker LM, Tan M, Suntharalingam M, Goloubeva O, Strome SE, Haddad RI, Patel SS, Cambell EV, Sarlis N, Lorch J, Cullen KJ |title=Racial survival disparity in head and neck cancer results from low prevalence of human papillomavirus infection in black oropharyngeal cancer patients |journal=Cancer Prev Res (Phila) |volume=2 |issue=9 |pages=776–81 |date=September 2009 |pmid=19641042 |pmc=4459126 |doi=10.1158/1940-6207.CAPR-09-0149 |url=}}</ref><ref name="pmid23386565">{{cite journal |vauthors=DeSantis C, Naishadham D, Jemal A |title=Cancer statistics for African Americans, 2013 |journal=CA Cancer J Clin |volume=63 |issue=3 |pages=151–66 |date=May 2013 |pmid=23386565 |doi=10.3322/caac.21173 |url=}}</ref>
* Shown below is a table depicting the age-adjusted [[prevalence]] of laryngeal cancer by race in 2011 in the United States.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>


{| style="cellpadding=0; cellspacing= 0; width: 600px;"
{| style="cellpadding=0; cellspacing= 0; width: 600px;"
|-
|-
|style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center | || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''All Races''' ||style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''White''' || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''Black''' || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''Asian/Pacific Islander'''  || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''Hispanic'''  
| style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" | || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''All Races''' || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''White''' || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''Black''' || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''Asian/Pacific Islander'''  || style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''Hispanic'''  
|-
|-
| style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align=center |'''Age-adjusted [[prevalence]]'''|| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |19.5 per 100,000 ||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |20.5 per 100,000 ||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |26.3 per 100,000 ||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |8.8 per 100,000 ||style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left |15 per 100,000
| style="padding: 0 5px; font-size: 100%; background: #4682B4; color: #FFFFFF; width: 10%" align="center" |'''Age-adjusted [[prevalence]]'''|| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align="left" |19.5 per 100,000 || style="font-size: 100; padding: 0 5px; background: #B8B8B8" align="left" |20.5 per 100,000 || style="font-size: 100; padding: 0 5px; background: #B8B8B8" align="left" |26.3 per 100,000 || style="font-size: 100; padding: 0 5px; background: #B8B8B8" align="left" |8.8 per 100,000 || style="font-size: 100; padding: 0 5px; background: #B8B8B8" align="left" |15 per 100,000
|}
|}


* Shown below is an image depicting the [[incidence]] of laryngeal cancer by race in the United States between 1975 and 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>
* Shown below is an image depicting the [[incidence]] of [[laryngeal cancer]] by [[race]] in the United States between 1975 and 2011.<ref name="SEER">Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.</ref>


[[Image:Incidence of laryngeal cancer by race in USA.PNG|[[Incidence]] of laryngeal cancer by race in the United States between 1975 and 2011]]
[[Image:Incidence of laryngeal cancer by race in USA.PNG|[[Incidence]] of laryngeal cancer by race in the United States between 1975 and 2011]]
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Latest revision as of 06:11, 18 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2], Rim Halaby, M.D. [3], Faizan Sheraz, M.D. [4]

Overview

The prevalence of laryngeal cancer is approximately 19.5 per 100,000 individuals in the United States. The incidence of laryngeal cancer is approximately 3.3 per 100,000 individuals in the United States. The estimated number of new cases in the United States in 2014 is 12,630 which corresponds to 0.8% of all new cancer cases. Laryngeal cancer is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH), which means that laryngeal cancer affects less than 200,000 people in the US population. In the United Kingdom, 2,369 people were diagnosed with laryngeal cancer in 2011.

Epidemiology and Demographics

Prevalence

Incidence

Age

Genetics

Loss of chromosomes 3p, 5q, 8p, 9p, 18q and 21q have been reported in laryngeal cancer[6]

Gender

  • In the United States, the age-adjusted prevalence of laryngeal cancer by gender in 2011 was:[1]
    • In males: 35.8 per 100,000
    • In females: 6.6 per 100,000
  • In the United States, the delay-adjusted incidence of laryngeal cancer by gender in 2011 was:[1]
    • In males: 5.28 per 100,000 persons
    • In females: 1.1 per 100,000 persons
  • In the United States, the age-adjusted incidence of laryngeal cancer by gender on 2011 was:[1]
    • In males: 5.18 per 100,000 persons
    • In females: 1.08 per 100,000 persons
  • Shown below is an image depicting the delay-adjusted incidence and observed incidence of laryngeal cancer by gender and race in the United States between 1975 and 2011. These graphs are adapted from SEER: The Surveillance, Epidemiology, and End Results Program of the National Cancer Institute.[1]

Delay-adjusted incidence and observed incidence of laryngeal cancer by gender and race in the United States between 1975 and 2011

Race

All Races White Black Asian/Pacific Islander Hispanic
Age-adjusted prevalence 19.5 per 100,000 20.5 per 100,000 26.3 per 100,000 8.8 per 100,000 15 per 100,000

Incidence of laryngeal cancer by race in the United States between 1975 and 2011

API: Asian/Pacific Islander; AI/AN: American Indian/ Alaska Native

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.
  2. ↑ 2.0 2.1 Lambert R, Sauvaget C, de Camargo Cancela M, Sankaranarayanan R (August 2011). "Epidemiology of cancer from the oral cavity and oropharynx". Eur J Gastroenterol Hepatol. 23 (8): 633–41. doi:10.1097/MEG.0b013e3283484795. PMID 21654320.
  3. ↑ 3.0 3.1 Siegel RL, Miller KD, Jemal A (January 2017). "Cancer Statistics, 2017". CA Cancer J Clin. 67 (1): 7–30. doi:10.3322/caac.21387. PMID 28055103.
  4. ↑ 4.0 4.1 Bray F, Ren JS, Masuyer E, Ferlay J (March 2013). "Global estimates of cancer prevalence for 27 sites in the adult population in 2008". Int. J. Cancer. 132 (5): 1133–45. doi:10.1002/ijc.27711. PMID 22752881.
  5. ↑ Cancer research UK
  6. ↑ de Miguel-Luken MJ, Chaves-Conde M, Carnero A (May 2016). "A genetic view of laryngeal cancer heterogeneity". Cell Cycle. 15 (9): 1202–12. doi:10.1080/15384101.2016.1156275. PMID 26940775.
  7. ↑ Settle K, Posner MR, Schumaker LM, Tan M, Suntharalingam M, Goloubeva O, Strome SE, Haddad RI, Patel SS, Cambell EV, Sarlis N, Lorch J, Cullen KJ (September 2009). "Racial survival disparity in head and neck cancer results from low prevalence of human papillomavirus infection in black oropharyngeal cancer patients". Cancer Prev Res (Phila). 2 (9): 776–81. doi:10.1158/1940-6207.CAPR-09-0149. PMC 4459126. PMID 19641042.
  8. ↑ DeSantis C, Naishadham D, Jemal A (May 2013). "Cancer statistics for African Americans, 2013". CA Cancer J Clin. 63 (3): 151–66. doi:10.3322/caac.21173. PMID 23386565.


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