Group B streptococcal infection pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
===Virulence Factor=== | |||
The polysaccharide antiphagocytic capsule is this bacterium's main [[virulence factor]]. | |||
===GBS in Pregnancy=== | ===Transmission=== | ||
====GBS in Pregnancy==== | |||
The gastrointestinal tract serves as the primary reservoir for GBS and is the likely source of vaginal colonization. | The gastrointestinal tract serves as the primary reservoir for GBS and is the likely source of vaginal colonization. | ||
===GBS in Neonates=== | ====GBS in Neonates==== | ||
Early-onset infections are acquired vertically through exposure to GBS from the vagina of a colonized woman. Neonatal infection occurs primarily when GBS ascends from the vagina to the amniotic fluid after onset of labor or rupture of membranes, although GBS also can invade through intact membranes | Early-onset infections are acquired vertically through exposure to GBS from the vagina of a colonized woman. Neonatal infection occurs primarily when GBS ascends from the vagina to the amniotic fluid after onset of labor or rupture of membranes, although GBS also can invade through intact membranes. GBS can be aspirated into the fetal lungs, which in turn can lead to bacteremia. Infants also can become infected with GBS during passage through the birth canal; infants who are exposed to the organism through this route can become colonized at mucus membrane sites in the gastrointestinal or respiratory tracts, but these colonized infants most commonly remain healthy. | ||
==References== | ==References== | ||
Revision as of 13:47, 21 August 2014
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Group B Streptococcal Infection Microchapters |
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Differentiating Group B Streptococcal Infection from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Group B streptococcal infection pathophysiology On the Web |
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American Roentgen Ray Society Images of Group B streptococcal infection pathophysiology |
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Directions to Hospitals Treating Group B streptococcal infection |
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Risk calculators and risk factors for Group B streptococcal infection pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Pathophysiology
Virulence Factor
The polysaccharide antiphagocytic capsule is this bacterium's main virulence factor.
Transmission
GBS in Pregnancy
The gastrointestinal tract serves as the primary reservoir for GBS and is the likely source of vaginal colonization.
GBS in Neonates
Early-onset infections are acquired vertically through exposure to GBS from the vagina of a colonized woman. Neonatal infection occurs primarily when GBS ascends from the vagina to the amniotic fluid after onset of labor or rupture of membranes, although GBS also can invade through intact membranes. GBS can be aspirated into the fetal lungs, which in turn can lead to bacteremia. Infants also can become infected with GBS during passage through the birth canal; infants who are exposed to the organism through this route can become colonized at mucus membrane sites in the gastrointestinal or respiratory tracts, but these colonized infants most commonly remain healthy.