Group B streptococcal infection medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | ==Medical Therapy in Meningitis== | ||
===Empirical Antibiotic Therapy in Neonatal Meningitis=== | ===Empirical Antibiotic Therapy in Neonatal Meningitis=== | ||
GBS should be suspected as a causative agent for bacterial meningitis in infants less than two years of age for whom empirical antibiotic therapy should be initiated immediately. | GBS should be suspected as a causative agent for bacterial meningitis in infants less than two years of age for whom empirical antibiotic therapy should be initiated immediately. | ||
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| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left | [[Ampicillin]] <br> OR<br> [[Penicillin]] <br> ''Consider adding an [[aminoglycoside]]''|| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left | Third generation cephalosporin <br> ([[Ceftriaxone]] or [[cefotaxime]]) | | style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left | [[Ampicillin]] <br> OR<br> [[Penicillin]] <br> ''Consider adding an [[aminoglycoside]]''|| style="font-size: 100; padding: 0 5px; background: #B8B8B8" align=left | Third generation cephalosporin <br> ([[Ceftriaxone]] or [[cefotaxime]]) | ||
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===Recommended Dosage of Antibiotics=== | |||
{| | |||
| '''Antibiotic agent''' || '''Dosage''' | |||
|- | |||
| [[Ampicillin]] || 0-7 days: 150 mg/kg <br> 8-28 days: 200 mg/kg <br> Infants > 28 days: 300 mg/kg | |||
|- | |||
| [[Cefotaxime]] || | |||
|- | |||
| [[Ceftriaxone]] || | |||
|- | |||
| [[Gentamicin]] || | |||
|- | |||
| [[Amikacin]] || | |||
|- | |||
| [[Tobramycin || | |||
|- | |||
| [[Penicillin]] || | |||
|- | |||
| [[Vancomycin]] || | |||
|- | |||
| [[Ceftriaxone]] || | |||
|- | |||
| [[Ceftazidime]] || | |||
|- | |- | ||
|} | |} | ||
Revision as of 21:44, 19 August 2014
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Group B Streptococcal Infection Microchapters |
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Differentiating Group B Streptococcal Infection from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Group B streptococcal infection medical therapy On the Web |
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American Roentgen Ray Society Images of Group B streptococcal infection medical therapy |
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Directions to Hospitals Treating Group B streptococcal infection |
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Risk calculators and risk factors for Group B streptococcal infection medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Medical Therapy in Meningitis
Empirical Antibiotic Therapy in Neonatal Meningitis
GBS should be suspected as a causative agent for bacterial meningitis in infants less than two years of age for whom empirical antibiotic therapy should be initiated immediately.
| Age | Possible pathogens causing the bacterial meningitis | Empirical treatment |
| < 1 month | Streptococcus agalactiae Escherichia coli Listeria monocytogenes Klebsiella |
Ampicillin + cefotaxime OR Ampicillin + aminoglycoside |
| 1-23 months | Streptococcus pneumoniae Neisseria meningitidis Streptococcus agalactiae Haemophilus influenzae E. coli |
Vancomycin + third generation cephalosporin |
Targeted Antibiotic Therapy in Neonatal Meningitis
| Recommended therapy for GBS meningitis | Alternative therapy for GBS meningitis |
| Ampicillin OR Penicillin Consider adding an aminoglycoside |
Third generation cephalosporin (Ceftriaxone or cefotaxime) |
Recommended Dosage of Antibiotics
| Antibiotic agent | Dosage |
| Ampicillin | 0-7 days: 150 mg/kg 8-28 days: 200 mg/kg Infants > 28 days: 300 mg/kg |
| Cefotaxime | |
| Ceftriaxone | |
| Gentamicin | |
| Amikacin | |
| [[Tobramycin | |
| Penicillin | |
| Vancomycin | |
| Ceftriaxone | |
| Ceftazidime |