Ebola medical therapy: Difference between revisions

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==Overview==
==Overview==
No specific [[antiviral drug]] has demonstrated effectiveness against Ebola infection.  Management is primarily supportive and symptomatic.  The following basic interventions, when used early, can significantly improve the chances of survival: providing [[intravenous fluid]]s (IV) and balancing [[electrolyte]]s (body salts), maintaining oxygen status and [[blood pressure]], and treating other infections if they occur.  Some organizations have suggested the addition of broad-spectrum antimicrobials, particularly in patients with evidence of septic shock.
No specific [[antiviral drug]] has demonstrated effectiveness against Ebola infection.  Management is primarily supportive and symptomatic.  The following basic interventions, when used early, can significantly improve the chances of survival: providing [[intravenous fluid]]s and balancing [[electrolyte]]s, maintaining oxygen status and [[blood pressure]], and treating other infections if they occur.  Some organizations have suggested the addition of broad-spectrum antimicrobials, particularly in patients with evidence of septic shock.


==Medical Therapy==
==Medical Therapy==

Revision as of 17:49, 1 October 2014

Ebola Microchapters

Home

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Ebola from other Diseases

Epidemiology and Demographics

Risk Factors

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Algorithm for the Evaluation of the Returned Traveler

Emergency Department Evaluation

Case Definition

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Hospital Preparedness

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Air Medical Transport

Monitoring and Movement Following Exposure

Primary Prevention

Future or Investigational Therapies

Postmortem Care

Postmortem Care

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Case #1

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NICE Guidance

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Directions to Hospitals Treating ebola

Risk calculators and risk factors for Ebola medical therapy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2]

Overview

No specific antiviral drug has demonstrated effectiveness against Ebola infection. Management is primarily supportive and symptomatic. The following basic interventions, when used early, can significantly improve the chances of survival: providing intravenous fluids and balancing electrolytes, maintaining oxygen status and blood pressure, and treating other infections if they occur. Some organizations have suggested the addition of broad-spectrum antimicrobials, particularly in patients with evidence of septic shock.

Medical Therapy

There are no targeted antiviral therapies currently in use. Treatment for Ebola is primarily supportive.

Bleeding

Replete coagulation factors with fresh frozen plasma if available, and transfuse with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding.

Dehydration

Replete with intravenous fluids with careful consideration of electrolyte imbalances.

Shock

Treat with a combination of intravenous fluids, vasopressors, and blood products as needed.

Hypoxia

Treat with supplemental oxygen including intubation if deemed necessary.

Superimposed Infections

Treating any complicating infections with empiric antibiotics.

References


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