MOPP regimen: Difference between revisions

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Revision as of 18:07, 27 March 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Mechlorethamine/Prednisone/Procarbazine/Vincristine Regimen; MOPP; MOPP Regimen; MOPP regimen; Mustargen-Oncovin-Procarbazine-Prednisone Regimen; NM/PCB/PRED/VCR

Overview

MOPP regimen refers to a chemotherapy regimen consisting of mechlorethamine, vincristine (Oncovin), procarbazine and prednisone, used alone or in combination with radiation therapy for the treatment of stage I-IV Hodgkin lymphoma. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen.^[1]^[2]

Regimen

MMechlorethamine

OVincristine (Oncovin)

PProcarbazine

PPrednisone

Indications

Stage I-IV Hodgkin lymphoma^[1]^[3]

References

↑ ^1.0 ^1.1 Filatova LV, Plotnikova AA, Gershanovich ML, Semiglazova TIu (2013). "[Effectiveness and toxicity of MOPP, ABVD, BEACOPP chemotherapy in first-diagnosed Hodgkin lymphoma with a poor prognosis]". Vopr Onkol. 59 (2): 59–65. PMID 23814851.
↑ "NCI Thesaurus".
↑ "NCI Thesaurus".

[pmid23814851-1] 1.0 ^1.1 Filatova LV, Plotnikova AA, Gershanovich ML, Semiglazova TIu (2013). "[Effectiveness and toxicity of MOPP, ABVD, BEACOPP chemotherapy in first-diagnosed Hodgkin lymphoma with a poor prognosis]". Vopr Onkol. 59 (2): 59–65. PMID 23814851.

[2] "NCI Thesaurus".

[3] "NCI Thesaurus".

[1]

[2]

[3]

@@ Line 6: / Line 6: @@
 ==Overview==
-{{PAGENAME}} refers to a chemotherapy regimen consisting of [[mechlorethamine]], [[vincristine|vincristine (Oncovin)]], [[procarbazine]] and [[prednisone]], used alone or in combination with radiation therapy for the treatment of stage I-IV [[Hodgkin lymphoma]]. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen.
+{{PAGENAME}} refers to a chemotherapy regimen consisting of [[mechlorethamine]], [[vincristine|vincristine (Oncovin)]], [[procarbazine]] and [[prednisone]], used alone or in combination with radiation therapy for the treatment of stage I-IV [[Hodgkin lymphoma]]. Due to the increased risk of gonadal toxicity, this regimen has been widely replaced by the ABVD regimen.<ref name="pmid23814851">{{cite journal| author=Filatova LV, Plotnikova AA, Gershanovich ML, Semiglazova TIu| title=[Effectiveness and toxicity of MOPP, ABVD, BEACOPP chemotherapy in first-diagnosed Hodgkin lymphoma with a poor prognosis]. | journal=Vopr Onkol | year= 2013 | volume= 59 | issue= 2 | pages= 59-65 | pmid=23814851 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23814851  }} </ref><ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C9619&ns=NCI_Thesaurus }}</ref>
 ==Regimen==
 {{chemo|M|Mechlorethamine}}
-{{chemo|O|vincristine (Oncovin)}}
-{{chemo|x|xx}}
-{{chemo|x|xx}}
+{{chemo|O|Vincristine (Oncovin)}}
+{{chemo|P|Procarbazine}}
+{{chemo|P|Prednisone}}
 ==Indications==
+*Stage I-IV [[Hodgkin lymphoma]]<ref name="pmid23814851">{{cite journal| author=Filatova LV, Plotnikova AA, Gershanovich ML, Semiglazova TIu| title=[Effectiveness and toxicity of MOPP, ABVD, BEACOPP chemotherapy in first-diagnosed Hodgkin lymphoma with a poor prognosis]. | journal=Vopr Onkol | year= 2013 | volume= 59 | issue= 2 | pages= 59-65 | pmid=23814851 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23814851  }} </ref><ref>{{Cite web | title = NCI Thesaurus | accessdate =  | url = http://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C9619&ns=NCI_Thesaurus }}</ref>
 ==References==