Lung cancer laboratory tests

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Saarah T. Alkhairy, M.D.

Overview

The laboratory findings associated with lung cancer are the following: neutropenia, hyponatremia, hypokalemia, hypercalcemia, respiratory acidosis, hypercarbia, hypoxia, and tumor cells in sputum and pleural effusion cytology.

Tests

• CBC

• Neutropenia in patients with a recent history of chemotherapy

• Serum electrolytes

• Hyponatremia from Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
• Hypokalemia from Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

• Hypercalcemia with normal PTH levels from squamous cell carcinoma (from secretion of parathyroid hormone-related peptide (PTH-rP))

• ABG

• Respiratory acidosis from respiratory failure
• Hypercarbia from respiratory failure
• Hypoxia from respiratory failure

• Sputum cytology

• Sputum cytology demonstrates tumor cells

• Needle thoracentesis

• Pleural effusion cytology demonstrates tumor cells