Endometrial cancer differential diagnosis: Difference between revisions

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Revision as of 15:14, 2 September 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shankar Kumar, M.B.B.S. [2]]

Overview

Differentiating Endometrial Cancer From Other Diseases

In early disease, uterine cancer must be differentiated from other diseases causing endometrial thickening:

benign endometrial proliferation
endometrial hyperplasia
endometrial polyp
submucosal uterine leiomyoma

Differential considerations for advanced lesions include:

uterine sarcoma(s)

endometrial stromal sarcoma (ESS)
leiomyosarcoma of the uterus
malignant mixed Mullerian tumour (MMMT) of the uterus

uterine lymphoma: rare

primary uterine lymphoma
secondary uterine involvement with lymphoma

cervical cancer with uterine invasion
metastasis to the uterus from a non gynaecologcial malignancy: rare

References

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@@ Line 5: / Line 5: @@
 ==Overview==
 ==Differentiating Endometrial Cancer From Other Diseases==
-*[[Endometrial hyperplasia]] - A [[post menopausal]] female will have same clinical history and examination making this condition indistinguishable from cancer. [[Biopsy]] is the only way to tell them apart.
+* In early disease, uterine cancer must be differentiated from other diseases causing endometrial thickening:
-*[[Endometrial polyp]] - Usually asymptomatic, but even if symptomatic, history is the same as cancer. [[Transvaginal]] [[ultrasound]] and [[saline]] infusion [[hysterosalpinogram]] can demonstrate the polyp.
+:* benign endometrial proliferation
-*[[Endometriosis]] - Common in pre-menopausal females; typical features like pelvic pain, [[dyspareunia]] and nodularity of [[utero-sacral ligament]] are present; Ultrasound will demonstrate [[endometrioma]]
+:* endometrial hyperplasia
-* [[Cervical cancer]] - patient is younger, without a history of prior [[Pap smear]], presenting with [[post-coital bleeding]] and an [[exophytic]] growth; [[colposcopy]] and biopsy to establish the diagnosis.
+:* endometrial polyp
-*[[Pyometria]] - typical history would be a [[febrile]] patient with recent cervical surgery with an enlarged, tender uterus; Ultrasound will demonstrate fluid inside the uterus.
+:* submucosal uterine leiomyoma
-* Uterine sarcomas
+* Differential considerations for advanced lesions include:
+:* uterine sarcoma(s)
+::* endometrial stromal sarcoma (ESS)
+::* leiomyosarcoma of the uterus
+::* malignant mixed Mullerian tumour (MMMT) of the uterus
+:* uterine lymphoma: rare
+::* primary uterine lymphoma
+::* secondary uterine involvement with lymphoma
+:* cervical cancer with uterine invasion
+:* metastasis to the uterus from a non gynaecologcial malignancy: rare
 ==References==

Endometrial cancer differential diagnosis: Difference between revisions

Revision as of 15:14, 2 September 2015

Overview

Differentiating Endometrial Cancer From Other Diseases

References

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