Hepatoblastoma medical therapy: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hepatoblastoma}} | {{Hepatoblastoma}} | ||
{{CMG}};{{AE}} {{NM}} | |||
{{CMG}} | |||
==Overview== | ==Overview== | ||
==Medical Therapy== | |||
Surgical resection, [[adjuvant chemotherapy]] prior to resection have been used to treat hepatoblastoma.<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | |||
*[[Chemotherapy]] has been proven effective in both an adjuvant and neoadjuvant treatment and can shrink tumors. | |||
*It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections. | |||
*Hepatoblastoma is sensitive to such chemotherapy drugs as [[doxorubicin]], [[cisplatin]], [[vincristine]], [[5-Fluorouracil]] and [[cyclophosphamide]]. | |||
==References== | ==References== | ||
Revision as of 19:35, 4 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Medical Therapy
Surgical resection, adjuvant chemotherapy prior to resection have been used to treat hepatoblastoma.[1]
- Chemotherapy has been proven effective in both an adjuvant and neoadjuvant treatment and can shrink tumors.
- It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections.
- Hepatoblastoma is sensitive to such chemotherapy drugs as doxorubicin, cisplatin, vincristine, 5-Fluorouracil and cyclophosphamide.
References
- ↑ Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.