Lung cancer history and symptoms: Difference between revisions
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{{Lung cancer}} | {{Lung cancer}} | ||
{{CMG}}; '''Associate Editor(s)-In-Chief:''' Kim-Son H. Nguyen, M.D., M.P.A., Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, {{CZ}} | {{CMG}}; '''Associate Editor(s)-In-Chief:''' Kim-Son H. Nguyen, M.D., M.P.A., Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, {{CZ}} | ||
==Overview== | ==Overview== | ||
common symptoms of lung cancer include [[dyspnea]], [[hemoptysis]], chronic [[coughing]], [[chest pain]], [[cachexia]], and [[dysphonia]].<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref> | |||
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==Symptoms== | ==Symptoms== | ||
[[Symptom]]s that suggest lung cancer include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref> | [[Symptom]]s that suggest lung cancer include:<ref name="Hamilton">{{cite journal | last =Hamilton | first =W | coauthors = Peters TJ, Round A, Sharp D | title =What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study | journal =Thorax | volume =60 | issue=12 | pages =1059–1065 | publisher = BMJ Publishing Group Ltd. | date =Dec 2005 | pmid =16227326 }}</ref> | ||
* [[Dyspnea]] ([[shortness of breath]]) | * [[Dyspnea]] ([[shortness of breath]]) | ||
* [[Hemoptysis]] | * [[Hemoptysis]] | ||
* Chronic [[coughing]] or change in regular coughing pattern | * Chronic [[coughing]] or change in regular coughing pattern | ||
* [[Wheezing]] | * [[Wheezing]] | ||
* [[Chest pain]] or pain in the abdomen | * [[Chest pain]] or pain in the abdomen | ||
* [[Cachexia]] (weight loss), [[Fatigue (physical)|fatigue]] and loss of [[appetite]] | * [[Cachexia]] (weight loss), [[Fatigue (physical)|fatigue]] and loss of [[appetite]] | ||
* [[Dysphonia]] | * [[Dysphonia]] | ||
* [[Dysphagia]] | * [[Dysphagia]] | ||
If the cancer grows in the [[airway]], it may obstruct airflow, causing [[dyspnea|breathing difficulties]]. This can lead to accumulation of secretions behind the blockage, predisposing the patient to [[pneumonia]]. | If the cancer grows in the [[airway]], it may obstruct airflow, causing [[dyspnea|breathing difficulties]]. This can lead to accumulation of secretions behind the blockage, predisposing the patient to [[pneumonia]]. | ||
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Many lung cancers have a rich blood supply. The surface of the cancer may be fragile, leading to bleeding from the cancer into the airway. This blood may subsequently be coughed up. | Many lung cancers have a rich blood supply. The surface of the cancer may be fragile, leading to bleeding from the cancer into the airway. This blood may subsequently be coughed up. | ||
Depending on the type of tumor, so-called [[Paraneoplastic phenomenon|paraneoplastic phenomena]] may initially attract attention to the disease.<ref name="Honnorat">{{cite journal | last =Honnorat | first = J | coauthors = Antoine JC | title = Paraneoplastic neurological syndromes | journal = Orphanet Journal of Rare Diseases | volume =2 | pages =22 | publisher = BioMed Central Ltd. | date = May 2007 | url=http://www.ojrd.com/content/2/1/22 | pmid =17480225 | doi=10.1186/1750-1172-2-22 | accessdate =2007-09-05 }}</ref> In lung cancer, these phenomena may include [[Lambert-Eaton myasthenic syndrome]] (muscle weakness due to [[autoimmune disorder|auto-antibodies]]), [[hypercalcemia]] or [[syndrome of inappropriate antidiuretic hormone]] (SIADH). Tumors in the top (apex) of the lung, known as [[Pancoast tumor]]s,<ref name="Jones">{{cite journal | last =Jones | first =DR | coauthors =Detterbeck FC | title =Pancoast tumors of the lung | journal =Current Opinion in Pulmonary Medicine | volume =4 | issue =4 | pages =191–197 | date =Jul 1998 | pmid =10813231 }}</ref> may invade the local part of the [[sympathetic nervous system]], leading to changed sweating patterns and eye muscle problems (a combination known as [[Horner's syndrome]]), as well as [[muscle weakness]] in the hands due to invasion of the [[brachial plexus]]. | Depending on the type of tumor, so-called [[Paraneoplastic phenomenon|paraneoplastic phenomena]] may initially attract attention to the disease.<ref name="Honnorat">{{cite journal | last =Honnorat | first = J | coauthors = Antoine JC | title = Paraneoplastic neurological syndromes | journal = Orphanet Journal of Rare Diseases | volume =2 | pages =22 | publisher = BioMed Central Ltd. | date = May 2007 | url=http://www.ojrd.com/content/2/1/22 | pmid =17480225 | doi=10.1186/1750-1172-2-22 | accessdate =2007-09-05 }}</ref> In lung cancer, these phenomena may include [[Lambert-Eaton myasthenic syndrome]] (muscle weakness due to [[autoimmune disorder|auto-antibodies]]), [[hypercalcemia]] or [[syndrome of inappropriate antidiuretic hormone]] (SIADH). | ||
Tumors in the top (apex) of the lung, known as [[Pancoast tumor]]s,<ref name="Jones">{{cite journal | last =Jones | first =DR | coauthors =Detterbeck FC | title =Pancoast tumors of the lung | journal =Current Opinion in Pulmonary Medicine | volume =4 | issue =4 | pages =191–197 | date =Jul 1998 | pmid =10813231 }}</ref> may invade the local part of the [[sympathetic nervous system]], leading to changed sweating patterns and eye muscle problems (a combination known as [[Horner's syndrome]]), as well as [[muscle weakness]] in the hands due to invasion of the [[brachial plexus]]. | |||
==References== | ==References== |
Revision as of 16:19, 15 December 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Kim-Son H. Nguyen, M.D., M.P.A., Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, Cafer Zorkun, M.D., Ph.D. [2]
Overview
common symptoms of lung cancer include dyspnea, hemoptysis, chronic coughing, chest pain, cachexia, and dysphonia.[1]
Symptoms
Symptoms that suggest lung cancer include:[1]
- Dyspnea (shortness of breath)
- Hemoptysis
- Chronic coughing or change in regular coughing pattern
- Wheezing
- Chest pain or pain in the abdomen
- Cachexia (weight loss), fatigue and loss of appetite
- Dysphonia
- Dysphagia
If the cancer grows in the airway, it may obstruct airflow, causing breathing difficulties. This can lead to accumulation of secretions behind the blockage, predisposing the patient to pneumonia.
Many lung cancers have a rich blood supply. The surface of the cancer may be fragile, leading to bleeding from the cancer into the airway. This blood may subsequently be coughed up.
Depending on the type of tumor, so-called paraneoplastic phenomena may initially attract attention to the disease.[2] In lung cancer, these phenomena may include Lambert-Eaton myasthenic syndrome (muscle weakness due to auto-antibodies), hypercalcemia or syndrome of inappropriate antidiuretic hormone (SIADH).
Tumors in the top (apex) of the lung, known as Pancoast tumors,[3] may invade the local part of the sympathetic nervous system, leading to changed sweating patterns and eye muscle problems (a combination known as Horner's syndrome), as well as muscle weakness in the hands due to invasion of the brachial plexus.
References
- ↑ 1.0 1.1 Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=
ignored (help) - ↑ Honnorat, J (May 2007). "Paraneoplastic neurological syndromes". Orphanet Journal of Rare Diseases. BioMed Central Ltd. 2: 22. doi:10.1186/1750-1172-2-22. PMID 17480225. Retrieved 2007-09-05. Unknown parameter
|coauthors=
ignored (help) - ↑ Jones, DR (Jul 1998). "Pancoast tumors of the lung". Current Opinion in Pulmonary Medicine. 4 (4): 191–197. PMID 10813231. Unknown parameter
|coauthors=
ignored (help)