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==Classification== | ==Classification== | ||
Hemophilia may be classified as severe, moderate or mild. This is based on the levels of Factor VIII or Factor IX depending on the type of hemophilia. | |||
*[[Haemophilia A]] is a recessive X-linked genetic disorder involving a lack of functional clotting Factor VIII and represents 80% of haemophilia cases. | *[[Haemophilia A]] is a recessive X-linked genetic disorder involving a lack of functional clotting Factor VIII and represents 80% of haemophilia cases. | ||
*[[Haemophilia B]] is a recessive X-linked genetic disorder involving a lack of functional clotting Factor IX. It comprises approximately 20% of haemophilia cases. | *[[Haemophilia B]] is a recessive X-linked genetic disorder involving a lack of functional clotting Factor IX. It comprises approximately 20% of haemophilia cases. |
Revision as of 15:21, 26 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Haemophilia may be classified into three subtypes:Haemophilia A , Haemophilia B, Haemophilia C.
Classification
Hemophilia may be classified as severe, moderate or mild. This is based on the levels of Factor VIII or Factor IX depending on the type of hemophilia.
- Haemophilia A is a recessive X-linked genetic disorder involving a lack of functional clotting Factor VIII and represents 80% of haemophilia cases.
- Haemophilia B is a recessive X-linked genetic disorder involving a lack of functional clotting Factor IX. It comprises approximately 20% of haemophilia cases.
- Haemophilia C is an autosomal genetic disorder (i.e. not X-linked) involving a lack of functional clotting Factor XI. Haemophilia C is not completely recessive, as heterozygous individuals also show increased bleeding