Hemophilia epidemiology and demographics: Difference between revisions
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===Haemophilia A=== | ===Haemophilia A=== | ||
The incidence of Haemophilia A is around 1 in 5000 male births. Approximately a third of affected individuals have no family history. Haemophilia A accounts for around 80% of cases. | The incidence of Haemophilia A is around 1 in 5000 male births. Approximately a third of affected individuals have no family history. Haemophilia A accounts for around 80% of cases. | ||
===Haemophilia=== | ===Haemophilia B=== | ||
It is the second-most common form of haemophilia, rarer than haemophilia A | |||
Haemophilia B (also known as Christmas disease) accounts for the remaining 20% of cases and results from a deficiency of coagulation Factor IX. The incidence of Haemophilia B is around 1 in 25,000 male births. | Haemophilia B (also known as Christmas disease) accounts for the remaining 20% of cases and results from a deficiency of coagulation Factor IX. The incidence of Haemophilia B is around 1 in 25,000 male births. | ||
===Haemophilia C=== | |||
Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes. However, it predominantly occurs in Jews of Ashkenazi descent. It is the fourth most common coagulation disorder after von Willebrand's disease and haemophilia A and B.[1] In the USA it is thought to affect 1 in 100,000 of the adult population, making it 10% as common as haemophilia A. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 14:11, 25 August 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Epidemiology and Demographics
About 18,000 people in the United States have haemophilia. Each year, about 400 babies are born with the disorder. Haemophilia usually occurs in males and less often in females.In the UK we now know that of every four baby boys born with Haemophilia, one will be born to a family with no previous history of the condition.
Haemophilia A
The incidence of Haemophilia A is around 1 in 5000 male births. Approximately a third of affected individuals have no family history. Haemophilia A accounts for around 80% of cases.
Haemophilia B
It is the second-most common form of haemophilia, rarer than haemophilia A Haemophilia B (also known as Christmas disease) accounts for the remaining 20% of cases and results from a deficiency of coagulation Factor IX. The incidence of Haemophilia B is around 1 in 25,000 male births.
Haemophilia C
Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes. However, it predominantly occurs in Jews of Ashkenazi descent. It is the fourth most common coagulation disorder after von Willebrand's disease and haemophilia A and B.[1] In the USA it is thought to affect 1 in 100,000 of the adult population, making it 10% as common as haemophilia A.