Testicular cancer overview: Difference between revisions
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'''Testicular cancer''' is [[cancer]] that develops in the [[testicle]]s, a part of the [[male]] reproductive system. | '''Testicular cancer''' is [[cancer]] that develops in the [[testicle]]s, a part of the [[male]] reproductive system. | ||
==Classification== | |||
Testicular cancer may be classified according to cell types into two subtypes: [[germ cell tumors]] and non–germ cell tumors. | |||
==Pathophysiology== | |||
On microscopic histopathological analysis of testicular cancer, fried-egg appearance is the characteristic finding of [[seminoma]]; marked nuclear atypia is the characteristic finding of [[embryonal carcinoma]]; blander cytomorphology, hyaline-type globules, and Schiller-Duval bodies are characteristic findings of [[yolk sac tumor ]]; syncytiotrophoblasts and cytotrophoblast cells are the characteristic findings of [[choriocarcinoma]]. | |||
==Causes== | |||
There are no known direct causes for testicular cancer. | |||
==Differential Diagnosis== | |||
Testicular cancer must be differentiated from [[epididymitis]], [[hematocele]], [[hydrocele]], [[spermatocele]], granulomatous [[orchitis]], and [[varicocele]]. | |||
==Epidemiology and Demographics== | |||
The [[prevalence]] of testicular cancer is approximately 88.1 per 100,000 males in the United States. The [[incidence]] of testicular cancer is approximately 5.88 per 100,000 males in the United States. The majority of cases are reported in New Zealand. Testicular cancer usually affects males of the white race. African American individuals are less likely to develop testicular cancer. | |||
==Risk Factors== | |||
Common risk factors in the development of testicular cancer are [[undescended testicle]], family history, personal history of testicular cancer, [[Klinefelter syndrome]]. | |||
==Screening== | |||
According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine [[screening]] for bladder cancer. | |||
==Prognosis== | |||
[[Prognosis]] of testicular cancer is generally good, and the 5-year survival rate is approximately 96.6%. | |||
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==References== | ==References== | ||
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[[Category:Andrology]] | [[Category:Andrology]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
Revision as of 17:56, 19 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Testicular cancer is cancer that develops in the testicles, a part of the male reproductive system.
Classification
Testicular cancer may be classified according to cell types into two subtypes: germ cell tumors and non–germ cell tumors.
Pathophysiology
On microscopic histopathological analysis of testicular cancer, fried-egg appearance is the characteristic finding of seminoma; marked nuclear atypia is the characteristic finding of embryonal carcinoma; blander cytomorphology, hyaline-type globules, and Schiller-Duval bodies are characteristic findings of yolk sac tumor ; syncytiotrophoblasts and cytotrophoblast cells are the characteristic findings of choriocarcinoma.
Causes
There are no known direct causes for testicular cancer.
Differential Diagnosis
Testicular cancer must be differentiated from epididymitis, hematocele, hydrocele, spermatocele, granulomatous orchitis, and varicocele.
Epidemiology and Demographics
The prevalence of testicular cancer is approximately 88.1 per 100,000 males in the United States. The incidence of testicular cancer is approximately 5.88 per 100,000 males in the United States. The majority of cases are reported in New Zealand. Testicular cancer usually affects males of the white race. African American individuals are less likely to develop testicular cancer.
Risk Factors
Common risk factors in the development of testicular cancer are undescended testicle, family history, personal history of testicular cancer, Klinefelter syndrome.
Screening
According to the the U.S. Preventive Service Task Force (USPSTF), there is insufficient evidence to recommend routine screening for bladder cancer.
Prognosis
Prognosis of testicular cancer is generally good, and the 5-year survival rate is approximately 96.6%.
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