Mantle cell lymphoma laboratory findings: Difference between revisions
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{{CMG}}; {{AE}} {{AS}} | {{CMG}}; {{AE}} {{AS}} | ||
==Overview== | ==Overview== | ||
Laboratory tests for mantle cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[cytogenetic analysis]], [[flow cytometry]], [[immunohistochemistry]], [[genetic testing]], [[FISH]], [[PCR]], and [[ | Laboratory tests for mantle cell lymphoma include [[complete blood count]] (CBC), blood chemistry studies, [[cytogenetic analysis]], [[flow cytometry]], [[immunohistochemistry]], [[genetic testing]], [[FISH]], [[PCR]], and [[immunophenotyping]]. | ||
==Laboratory tests== | ==Laboratory tests== | ||
Laboratory tests for mantle cell lymphoma include:<ref name=”seer”>National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref> | Laboratory tests for mantle cell lymphoma include:<ref name=”seer”>National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov</ref> | ||
Revision as of 13:37, 3 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Laboratory tests for mantle cell lymphoma include complete blood count (CBC), blood chemistry studies, cytogenetic analysis, flow cytometry, immunohistochemistry, genetic testing, FISH, PCR, and immunophenotyping.
Laboratory tests
Laboratory tests for mantle cell lymphoma include:[1]
- Complete blood count (CBC)
- Blood chemistry studies
- Cytogenetic analysis
- Flow cytometry
- Immunohistochemistry
- Genetic testing
- Heavy and light chain genes rearranged, t(11;14)(q13;q32) in virtually all cases
- Overexpression CYCLIN D mRNA
- Mutation or deletions of ATM gene
- Polymerase chain reaction (PCR) and CER3 clonotypic primers are additional methods, but are less often used.
References
- ↑ National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov