Mantle cell lymphoma laboratory findings: Difference between revisions
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Revision as of 02:30, 27 November 2017
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Mantle cell lymphoma Microchapters |
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Mantle cell lymphoma laboratory findings On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Laboratory tests for mantle cell lymphoma include complete blood count (CBC), blood chemistry studies, cytogenetic analysis, flow cytometry, immunohistochemistry, genetic testing, FISH, PCR, and immunophenotyping.
Laboratory tests
Laboratory tests for mantle cell lymphoma include:[1]
- Complete blood count (CBC)
- Blood chemistry studies
- Cytogenetic analysis
- Flow cytometry
- Immunohistochemistry
- Genetic testing
- Heavy and light chain genes rearranged, t(11;14)(q13;q32) in virtually all cases
- Overexpression CYCLIN D mRNA
- Mutation or deletions of ATM gene
- Polymerase chain reaction (PCR) and CER3 clonotypic primers are additional methods, but are less often used.
References
- ↑ National Cancer Institute. Surveillance, Epidemiology, and End Results Program 2015. http://seer.cancer.gov