Esophageal cancer pathophysiology: Difference between revisions
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*Cytology: | *Cytology: | ||
:*Nucleus - typical central | :*Nucleus - typical central | ||
:* | :*Mitoses may be present | ||
:*Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic) | :*Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic) | ||
* | *Squamous whorls may be present<ref>{{Cite web | title =Squamous cell carcinoma of the esophagus | ||
| url =http://librepathology.org/wiki/index.php/Squamous_cell_carcinoma_of_the_esophagus }}</ref> | | url =http://librepathology.org/wiki/index.php/Squamous_cell_carcinoma_of_the_esophagus }}</ref> | ||
Revision as of 13:01, 10 September 2015
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Esophageal cancer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Esophageal cancer pathophysiology On the Web |
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American Roentgen Ray Society Images of Esophageal cancer pathophysiology |
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Risk calculators and risk factors for Esophageal cancer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
The pathophysiology of esophageal cancer depends on the histological subtype.
Pathology
Microscopic pathology
Squamous cell carcinoma
Atypical squamous cells with invasion through the basement membrane:
- Cytology:
- Nucleus - typical central
- Mitoses may be present
- Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic)
- Squamous whorls may be present[1]
Adenocarcinoma
- Invading cell clusters or glands
- Cribriforming (more than rare) or desmoplasia or "deep" invasion (into submucosa)
- Nuclear atypia of malignancy:
- Size variation
- Shape variation
- Staining variation
- +/-Mitoses (common)[2]