Esophageal cancer pathophysiology: Difference between revisions
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| url =http://librepathology.org/wiki/index.php/Squamous_cell_carcinoma_of_the_esophagus }}</ref> | | url =http://librepathology.org/wiki/index.php/Squamous_cell_carcinoma_of_the_esophagus }}</ref> | ||
====Adenocarcinoma==== | ====Adenocarcinoma<ref>{{Cite web | title =Esophageal adenocarcinoma| url =http://librepathology.org/wiki/index.php/Esophageal_adenocarcinoma#Microscopic }}</ref>==== | ||
*Invading cell clusters or glands | *Invading cell clusters or glands | ||
:*Cribriforming (more than rare) or desmoplasia or "deep" invasion (into submucosa) | :*Cribriforming (more than rare) or desmoplasia or "deep" invasion (into submucosa) | ||
Line 25: | Line 25: | ||
:*Shape variation | :*Shape variation | ||
:*Staining variation | :*Staining variation | ||
*Mitoses (common) | *Mitoses (common) | ||
==References== | ==References== |
Revision as of 19:01, 10 September 2015
Esophageal cancer Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Esophageal cancer pathophysiology On the Web |
American Roentgen Ray Society Images of Esophageal cancer pathophysiology |
Risk calculators and risk factors for Esophageal cancer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
The pathophysiology of esophageal cancer depends on the histological subtype.
Pathology
Microscopic pathology
Squamous cell carcinoma
Atypical squamous cells with invasion through the basement membrane:
- Cytology:
- Nucleus - typical central
- Mitoses may be present
- Cytoplasm - "dense-appearing", typically eosinophilic (may be intensely eosinophilic)
- Squamous whorls may be present[1]
Adenocarcinoma[2]
- Invading cell clusters or glands
- Cribriforming (more than rare) or desmoplasia or "deep" invasion (into submucosa)
- Nuclear atypia of malignancy:
- Size variation
- Shape variation
- Staining variation
- Mitoses (common)