Prolactinoma natural history, complications, and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
If left untreated, 95% of cases of [[prolactinoma]] will not show any signs of growth during the first 4- to 6-year period. Complications of prolactinoma include [[intracranial hemorrhage]], [[osteoporosis]] and [[vision loss]]. Prognosis is generally excellent for cases of microprolactinoma. | |||
==Natural History== | ==Natural History== | ||
If left untreated, 95% of cases of [[prolactinoma]] will not show any signs of growth | If left untreated, 95% of cases of [[prolactinoma]] will not show any signs of growth during the first 4- to 6-year period. | ||
==Complications== | ==Complications== | ||
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*In pregnancy excessive [[estrogen]] may cause increased tumor growth | *In pregnancy excessive [[estrogen]] may cause increased tumor growth | ||
*[[Osteoporosis]] | *[[Osteoporosis]] | ||
==Prognosis== | |||
*Prognosis is excellent for cases of microprolactinoma. | |||
*Depending on the size of the tumor and the extent of tumor resection, the rate of recurrence may range from 20% to 50%. | |||
*The majority of recurrent prolactinomas develop within the first 5 years.<ref>http://www.niddk.nih.gov/health-information/health-topics/endocrine/prolactinoma/Pages/fact-sheet.aspx</ref> | |||
==References== | ==References== | ||
Revision as of 17:03, 15 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
If left untreated, 95% of cases of prolactinoma will not show any signs of growth during the first 4- to 6-year period. Complications of prolactinoma include intracranial hemorrhage, osteoporosis and vision loss. Prognosis is generally excellent for cases of microprolactinoma.
Natural History
If left untreated, 95% of cases of prolactinoma will not show any signs of growth during the first 4- to 6-year period.
Complications
Complications of prolactinoma include:
- Bleeding (intracranial)
- Tumor regrowth (after resection)
- Blindness
- In pregnancy excessive estrogen may cause increased tumor growth
- Osteoporosis
Prognosis
- Prognosis is excellent for cases of microprolactinoma.
- Depending on the size of the tumor and the extent of tumor resection, the rate of recurrence may range from 20% to 50%.
- The majority of recurrent prolactinomas develop within the first 5 years.[1]