Prolactinoma surgery: Difference between revisions
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*Medical therapy fails to reduce [[ prolactin]] levels | *Medical therapy fails to reduce [[ prolactin]] levels | ||
*Medical therapy fails to restore normal reproduction and [[pituitary]] function | *Medical therapy fails to restore normal reproduction and [[pituitary]] function | ||
*Medical therapy fails to reduce tumor size | *Medical therapy fails to reduce tumor size | ||
If medical therapy is only partially successful, it should be continued, possibly combined with surgery or [[radiation]]. | If medical therapy is only partially successful, it should be continued, possibly combined with surgery or [[radiation]]. | ||
===Transsphenoidal Resection=== | ===Transsphenoidal Resection=== | ||
Revision as of 14:11, 11 September 2015
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Prolactinoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Prolactinoma surgery On the Web |
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American Roentgen Ray Society Images of Prolactinoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Surgery is indicated in patients if medical therapy cannot be tolerated or if it fails to reduce prolactin levels, restore normal reproduction and pituitary function, and reduce tumor size. If medical therapy is only partially successful, this therapy should continue, possibly combined with surgery or radiation treatment.
Surgery
Surgery is indicated in patients if:
- Medical therapy cannot be tolerated
- Medical therapy fails to reduce prolactin levels
- Medical therapy fails to restore normal reproduction and pituitary function
- Medical therapy fails to reduce tumor size
If medical therapy is only partially successful, it should be continued, possibly combined with surgery or radiation.
Transsphenoidal Resection
Most often, the tumor is removed through the nasal cavity. Rarely, if the tumor is large or has spread to nearby brain tissue, the surgeon will access the tumor through an opening in the skull. The results of surgery depend on tumor size and prolactin concentrations. Surgery corrects prolactin concentrations in about 80 percent of patients with:
- Small tumors (microadenomas)
- Serum prolactin less than 200 nanograms per milliliter (ng/ml)