Glioblastoma multiforme pathophysiology: Difference between revisions
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*Genes involved in the pathogenesis of secondary glioblastoma include:<ref name=ddd>Pathology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | *Genes involved in the pathogenesis of secondary glioblastoma include:<ref name=ddd>Pathology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | ||
**'' | **''IDH1'' | ||
**''[[p53]]'' | **''[[p53]]'' | ||
** | **Chromosome 10q | ||
**Chromosome 17p | |||
**Chromosome 19q | |||
===Associated Conditions=== | ===Associated Conditions=== | ||
Revision as of 22:38, 12 September 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Pathophysiology
Genetics
- Development of glioblastoma is the result from multiple genetic mutations.
- Genes involved in the pathogenesis of primary glioblastoma include:[1]
- Genes involved in the pathogenesis of secondary glioblastoma include:[1]
- IDH1
- p53
- Chromosome 10q
- Chromosome 17p
- Chromosome 19q
Associated Conditions
Glioblastoma may be associated with:[1]
Gross Pathology
Microscopic Pathology
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Glioblastoma (histology slide)
.jpg)
References
- ↑ 1.0 1.1 1.2 Pathology of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma