Glioblastoma multiforme differential diagnosis: Difference between revisions

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Revision as of 14:37, 14 September 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Differentiating Glioblastoma multiforme from other Diseases

Glioblastoma must be differentiated from:^[1]


Differential diagnosis	Characteristic features

Cerebral metastasis	May look identical Both may appear multifocal Metastases are centred on grey-white matter junction and spare the overlying cortex
Primary CNS lymphoma	In patients with AIDS Central necrosis is more common Homogeneously enhancing on MRI
Cerebral abscess	Central restricted diffusion is helpful Hemorrhagic then assessment may be difficult Presence of smooth and complete SWI low intensity rim Presence of dual rim sign
Anaplastic astrocytoma	No central necrosis
Tumefactive demyelination	Can appear similar Open ring pattern of enhancement Younger patients
Stroke	History is suggestive of diagnosis No elevated choline
Cerebral toxoplasmosis	Seen in patients with AIDS
Radiation necrosis	Positive history of radiation
Encephalitis
Oligodendroglioma
Epilepsy

References

↑ DDx of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma

Template:WikiDoc Sources

[ddd-1] DDx of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma

[1]

@@ Line 15: / Line 15: @@
 |-
 | style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |
-:[[Cerebral metastasis]]
+:Cerebral [[metastasis]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *May look identical
 *Both may appear multifocal
-*Metastases are centred on grey-white matter junction and spare the overlying cortex
+*Metastases are centred on [[grey-white matter]] junction and spare the overlying [[cortex]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Primary CNS lymphoma
+:[[Primary CNS lymphoma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Seen in patients with AIDS
+*In patients with [[AIDS]]
-*Central necrosis is more common
+*[[Central necrosis]] is more common
-*Homogeneously enhancing on MRI
+*Homogeneously enhancing on [[MRI]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Cerebral abscess
+:[[Cerebral abscess]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Central restricted diffusion is helpful
-*Hemorrhagic then assessment may be difficult
+*[[Hemorrhagic]] then assessment may be difficult
 *Presence of smooth and complete SWI low intensity rim
 *Presence of dual rim sign
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Anaplastic astrocytoma
+:[[Anaplastic astrocytoma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*No central necrosis
+*No central [[necrosis]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Tumefactive demyelination
+:[[Tumefactive demyelination]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 *Can appear similar
@@ Line 49: / Line 49: @@
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Stroke
+:[[Stroke]]
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 *History is suggestive of diagnosis
@@ Line 55: / Line 55: @@
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Cerebral toxoplasmosis
+:[[Cerebral toxoplasmosis]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
-*Seen in patients with AIDS
+*Seen in patients with [[AIDS]]
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Radiation necrosis
+:[[Radiation necrosis]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
+*Positive history of radiation
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Encephalitis
+:[[Encephalitis]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Oligodendroglioma
+:[[Oligodendroglioma]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 |-
 | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" |
-:Seizures
+:[[Epilepsy]]
 | style="padding: 5px 5px; background: #F5F5F5;" |
 |-

Glioblastoma multiforme differential diagnosis: Difference between revisions

Revision as of 14:37, 14 September 2015

Overview

Differentiating Glioblastoma multiforme from other Diseases

References

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