Nasopharyngeal carcinoma epidemiology and demographics: Difference between revisions
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==Demographics== | ==Demographics== | ||
NPC is uncommon in the [[United States]] and most other nations, representing less than 1 case per 100,000 individuals.<ref name=WHO>{{cite web|url=http://www.who.int/vaccine_research/diseases/viral_cancers/en/index1.html|title=Initiative for Vaccine Research (IVR): Viral cancers|publisher=World Health Organization|accessdate=2 October 2012}}</ref> but is extremely common in [[Southern China|southern regions of China]],<ref name="pmid18570662">{{cite journal |author=Fang W, Li X, Jiang Q, |title=Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China |journal=J Transl Med |volume=6 |issue= |pages=32 |year=2008 |pmid=18570662 |pmc=2443113 |doi=10.1186/1479-5876-6-32 |url=http://www.translational-medicine.com/content/6//32 }}</ref> particularly in [[Guangdong]], accounting for 18% of all cancers in [[China]].<ref name="chang2006">{{cite journal |author=Chang E T, Adami H |title=The Enigmatic Epidemiology of Nasopharyngeal Carcinoma |journal=Cancer Epidemiol Biomarkers Prev |volume=15 |issue=10 |pages=1765–1777 |year=2006 |doi=10.1158/1055-9965.EPI-06-0353 |pmid=17035381}}</ref> | |||
NPC is uncommon in the United States and most other nations, but is extremely common in Taiwan and certain regions of China, accounting for 18% of all cancers in the latter nation. The cause of increased risk for [[NPC]] in these [[endemic (epidemiology)|endemic]] regions is not entirely clear.<ref name="Weidner's">{{cite book |author=Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor) |title=Modern Surgical Pathology (2 Volume Set) |publisher=W B Saunders |location=London |year= |pages= |isbn=0-7216-7253-1 |oclc= |doi=}}</ref> [[Nasopharyngeal carcinomas]] account for approximately 70% of all primary malignancies of the [[nasopharynx]], and although it is rare in western populations, it is one of the most common malignancies encountered in Asia, especially China.<ref>http://radiopaedia.org/articles/nasopharyngeal-carcinoma</ref> | NPC is uncommon in the United States and most other nations, but is extremely common in Taiwan and certain regions of China, accounting for 18% of all cancers in the latter nation. The cause of increased risk for [[NPC]] in these [[endemic (epidemiology)|endemic]] regions is not entirely clear.<ref name="Weidner's">{{cite book |author=Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor) |title=Modern Surgical Pathology (2 Volume Set) |publisher=W B Saunders |location=London |year= |pages= |isbn=0-7216-7253-1 |oclc= |doi=}}</ref> [[Nasopharyngeal carcinomas]] account for approximately 70% of all primary malignancies of the [[nasopharynx]], and although it is rare in western populations, it is one of the most common malignancies encountered in Asia, especially China.<ref>http://radiopaedia.org/articles/nasopharyngeal-carcinoma</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Nasopharyngeal carcinomas account for approximately 70% of all primary malignancies of the nasopharynx, and although it is rare in western populations, it is one of the most common malignancies encountered in Asia, especially China.
Epidemiology
Age
While NPC is seen primarily in middle-aged individuals in Asia, a high proportion of African cases appear in children.
Demographics
NPC is uncommon in the United States and most other nations, representing less than 1 case per 100,000 individuals.[1] but is extremely common in southern regions of China,[2] particularly in Guangdong, accounting for 18% of all cancers in China.[3] NPC is uncommon in the United States and most other nations, but is extremely common in Taiwan and certain regions of China, accounting for 18% of all cancers in the latter nation. The cause of increased risk for NPC in these endemic regions is not entirely clear.[4] Nasopharyngeal carcinomas account for approximately 70% of all primary malignancies of the nasopharynx, and although it is rare in western populations, it is one of the most common malignancies encountered in Asia, especially China.[5]
References
- ↑ "Initiative for Vaccine Research (IVR): Viral cancers". World Health Organization. Retrieved 2 October 2012.
- ↑ Fang W, Li X, Jiang Q, (2008). "Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China". J Transl Med. 6: 32. doi:10.1186/1479-5876-6-32. PMC 2443113. PMID 18570662.
- ↑ Chang E T, Adami H (2006). "The Enigmatic Epidemiology of Nasopharyngeal Carcinoma". Cancer Epidemiol Biomarkers Prev. 15 (10): 1765–1777. doi:10.1158/1055-9965.EPI-06-0353. PMID 17035381.
- ↑ Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1.
- ↑ http://radiopaedia.org/articles/nasopharyngeal-carcinoma