Glioblastoma multiforme surgery: Difference between revisions
Jump to navigation
Jump to search
| Line 9: | Line 9: | ||
Surgery is the mainstay of treatment for glioblastoma.<ref name=ddd>Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | Surgery is the mainstay of treatment for glioblastoma.<ref name=ddd>Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma</ref> | ||
*An average glioblastoma tumor contains 10<sup>11</sup> cells, which is reduced to 10<sup>9</sup> cells after surgery (a reduction of 99%). | *An average glioblastoma tumor contains 10<sup>11</sup> cells, which is reduced to 10<sup>9</sup> cells after surgery (a reduction of 99%). | ||
* | *Surgery is used to take a section for a pathological diagnosis, to remove some of the symptoms of a large mass pressing against the brain, to remove [[tumor]] before secondary resistance to [[radiotherapy]] and [[chemotherapy]], and to prolong survival. | ||
* | *Removal of 98% or more of the tumor has been associated with a better prognosis. | ||
*The chances of near-complete initial removal of the tumor can be greatly increased if the surgery is guided by a fluorescent dye | *The chances of near-complete initial removal of the tumor can be greatly increased if the surgery is guided by a fluorescent dye known as 5-aminolevulinic acid. | ||
*Glioblastoma tumor cells are widely infiltrative through the brain at diagnosis | *Glioblastoma tumor cells are widely infiltrative through the brain at diagnosis. Despite a near-total resection, majority of people with glioblastoma develop recurrence, either at the original site or at more distant satellite lesions within the brain. | ||
==References== | ==References== | ||
Revision as of 18:35, 16 September 2015
|
Glioblastoma multiforme Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Glioblastoma multiforme surgery On the Web |
|
American Roentgen Ray Society Images of Glioblastoma multiforme surgery |
|
Risk calculators and risk factors for Glioblastoma multiforme surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Surgery is the mainstay of treatment for glioblastoma.[1]
Surgery
Surgery is the mainstay of treatment for glioblastoma.[1]
- An average glioblastoma tumor contains 1011 cells, which is reduced to 109 cells after surgery (a reduction of 99%).
- Surgery is used to take a section for a pathological diagnosis, to remove some of the symptoms of a large mass pressing against the brain, to remove tumor before secondary resistance to radiotherapy and chemotherapy, and to prolong survival.
- Removal of 98% or more of the tumor has been associated with a better prognosis.
- The chances of near-complete initial removal of the tumor can be greatly increased if the surgery is guided by a fluorescent dye known as 5-aminolevulinic acid.
- Glioblastoma tumor cells are widely infiltrative through the brain at diagnosis. Despite a near-total resection, majority of people with glioblastoma develop recurrence, either at the original site or at more distant satellite lesions within the brain.
References
- ↑ 1.0 1.1 Treatment of glioblastoma multiforme. Dr Dylan Kurda and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/glioblastoma