Gliomatosis cerebri other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
Other imaging studies for gliomatosis cerebri include [[In vivo magnetic resonance spectroscopy|MR spectroscopy]] (decreased [[N-Acetylaspartic acid|NAA]]/[[creatine]] ratio and elevated [[choline]]/[[creatine]] ratio, [[choline]]/[[N-Acetylaspartic acid|NAA]] ratio, and [[myo-inositol|myoinositol]]), [[perfusion weighted imaging|MR perfusion]] (low/normal relative cerebral blood flow), [[PET scan]] (markedly decreased accumulation of [[Florbetapir (18F)|[18F]-fluorodeoxyglucose]] on [[PET|F-18 FDG PET]] images, [[hypermetabolism]] on [[PET|C-11 methionine PET]] images, and marked increase in cerebral blood flow on [[PET|15(O)-water PET]] images), and [[bone scan]] (metastasis to [[bones]]).<ref name=aaa>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid22740882">{{cite journal| author=Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR| title=Presentation patterns and outcome of gliomatosis cerebri. | journal=Oncol Lett | year= 2012 | volume= 3 | issue= 1 | pages= 209-213 | pmid=22740882 | doi=10.3892/ol.2011.445 | pmc=PMC3362440 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22740882 }} </ref> | Other imaging studies for gliomatosis cerebri include [[In vivo magnetic resonance spectroscopy|MR spectroscopy]] (decreased [[N-Acetylaspartic acid|NAA]]/[[creatine]] ratio and elevated [[choline]]/[[creatine]] ratio, [[choline]]/[[N-Acetylaspartic acid|NAA]] ratio, and [[myo-inositol|myoinositol]]), [[perfusion weighted imaging|MR perfusion]] (low/normal relative cerebral blood flow), [[PET scan]] (markedly decreased accumulation of [[Florbetapir (18F)|[18F]-fluorodeoxyglucose]] on [[PET|F-18 FDG PET]] images, [[hypermetabolism]] on [[PET|C-11 methionine PET]] images, and marked increase in cerebral blood flow on [[PET|15(O)-water PET]] images), and [[bone scan]] (metastasis to [[bones]]).<ref name=aaa>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid22740882">{{cite journal| author=Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR| title=Presentation patterns and outcome of gliomatosis cerebri. | journal=Oncol Lett | year= 2012 | volume= 3 | issue= 1 | pages= 209-213 | pmid=22740882 | doi=10.3892/ol.2011.445 | pmc=PMC3362440 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22740882 }} </ref><ref name="pmid20334921">{{cite journal| author=Desclée P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G| title=Gliomatosis cerebri, imaging findings of 12 cases. | journal=J Neuroradiol | year= 2010 | volume= 37 | issue= 3 | pages= 148-58 | pmid=20334921 | doi=10.1016/j.neurad.2009.12.001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20334921 }} </ref> | ||
==Other Imaging Findings== | ==Other Imaging Findings== | ||
Other imaging studies for gliomatosis cerebri include [[In vivo magnetic resonance spectroscopy|MR spectroscopy]] (elevated [[choline]]/[[creatine]] ratio, [[choline]]/[[N-Acetylaspartic acid|NAA]] ratio, and [[myo-inositol|myoinositol]]), [[perfusion weighted imaging|MR perfusion]] (low/normal relative cerebral blood flow), [[PET scan]] (markedly decreased accumulation of [[Florbetapir (18F)|[18F]-fluorodeoxyglucose]] on [[PET|F-18 FDG PET]] images, [[hypermetabolism]] on [[PET|C-11 methionine PET]] images, and marked increase in cerebral blood flow on [[PET|15(O)-water PET]] images), and [[bone scan]] (metastasis to [[bones]]).<ref name=aaa>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid22740882">{{cite journal| author=Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR| title=Presentation patterns and outcome of gliomatosis cerebri. | journal=Oncol Lett | year= 2012 | volume= 3 | issue= 1 | pages= 209-213 | pmid=22740882 | doi=10.3892/ol.2011.445 | pmc=PMC3362440 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22740882 }} </ref> | Other imaging studies for gliomatosis cerebri include [[In vivo magnetic resonance spectroscopy|MR spectroscopy]] (decreased [[N-Acetylaspartic acid|NAA]]/[[creatine]] ratio and elevated [[choline]]/[[creatine]] ratio, [[choline]]/[[N-Acetylaspartic acid|NAA]] ratio, and [[myo-inositol|myoinositol]]), [[perfusion weighted imaging|MR perfusion]] (low/normal relative cerebral blood flow), [[PET scan]] (markedly decreased accumulation of [[Florbetapir (18F)|[18F]-fluorodeoxyglucose]] on [[PET|F-18 FDG PET]] images, [[hypermetabolism]] on [[PET|C-11 methionine PET]] images, and marked increase in cerebral blood flow on [[PET|15(O)-water PET]] images), and [[bone scan]] (metastasis to [[bones]]).<ref name=aaa>Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri</ref><ref name="pmid22740882">{{cite journal| author=Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR| title=Presentation patterns and outcome of gliomatosis cerebri. | journal=Oncol Lett | year= 2012 | volume= 3 | issue= 1 | pages= 209-213 | pmid=22740882 | doi=10.3892/ol.2011.445 | pmc=PMC3362440 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22740882 }} </ref><ref name="pmid20334921">{{cite journal| author=Desclée P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G| title=Gliomatosis cerebri, imaging findings of 12 cases. | journal=J Neuroradiol | year= 2010 | volume= 37 | issue= 3 | pages= 148-58 | pmid=20334921 | doi=10.1016/j.neurad.2009.12.001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20334921 }} </ref> | ||
===1. MR Spectroscopy=== | ===1. MR Spectroscopy=== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Other imaging studies for gliomatosis cerebri include MR spectroscopy (decreased NAA/creatine ratio and elevated choline/creatine ratio, choline/NAA ratio, and myoinositol), MR perfusion (low/normal relative cerebral blood flow), PET scan (markedly decreased accumulation of [18F]-fluorodeoxyglucose on F-18 FDG PET images, hypermetabolism on C-11 methionine PET images, and marked increase in cerebral blood flow on 15(O)-water PET images), and bone scan (metastasis to bones).[1][2][3]
Other Imaging Findings
Other imaging studies for gliomatosis cerebri include MR spectroscopy (decreased NAA/creatine ratio and elevated choline/creatine ratio, choline/NAA ratio, and myoinositol), MR perfusion (low/normal relative cerebral blood flow), PET scan (markedly decreased accumulation of [18F]-fluorodeoxyglucose on F-18 FDG PET images, hypermetabolism on C-11 methionine PET images, and marked increase in cerebral blood flow on 15(O)-water PET images), and bone scan (metastasis to bones).[1][2][3]
1. MR Spectroscopy
Other imaging studies for gliomatosis cerebri include MR spectroscopy. Common findings are described below:[1][3]
- Decreased NAA/creatine ratio
- Elevated choline/creatine ratio
- Elevated choline/NAA ratio
- Elevated myoinositol
2. MR Perfusion
Other imaging studies for gliomatosis cerebri include MR perfusion. Common findings are described below:[1]
- Low/normal relative cerebral blood flow (no vascular hyperplasia)
3. PET
Other imaging studies for gliomatosis cerebri include PET scan. Common features are described below:[1][2]
- F-18 FDG PET images show markedly decreased accumulation of [18F]-fluorodeoxyglucose (glucose hypometabolism).
- C-11 methionine PET images show hypermetabolism.
- 15(O)-water PET images show a marked increase in cerebral blood flow in gliomatosis cerebri lesions.
4. Bone Scan
Bone scan may be performed to detect metastases of gliomatosis cerebri to bones.
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Radiographic features of gliomatosis cerebri. Dr Henry Knipe and Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/gliomatosis-cerebri
- ↑ 2.0 2.1 2.2 Rajz GG, Nass D, Talianski E, Pfeffer R, Spiegelmann R, Cohen ZR (2012). "Presentation patterns and outcome of gliomatosis cerebri". Oncol Lett. 3 (1): 209–213. doi:10.3892/ol.2011.445. PMC 3362440. PMID 22740882.
- ↑ 3.0 3.1 3.2 Desclée P, Rommel D, Hernalsteen D, Godfraind C, de Coene B, Cosnard G (2010). "Gliomatosis cerebri, imaging findings of 12 cases". J Neuroradiol. 37 (3): 148–58. doi:10.1016/j.neurad.2009.12.001. PMID 20334921.