Insulinoma medical therapy: Difference between revisions
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The predominant therapy for insulinoma is surgical resection. Supportive therapy for insulinoma includes octerotide, endoscopic ultrasound guided alcohol ablation, radiofrequency ablation, embolization, diazoxide and chemotherapy. | The predominant therapy for insulinoma is surgical resection. Supportive therapy for insulinoma includes octerotide, endoscopic ultrasound guided alcohol ablation, radiofrequency ablation, embolization, diazoxide and chemotherapy. | ||
==Medical Therapy== | ==Medical Therapy== | ||
The medical therapy of insulinoma include:<ref name="pmid23430217">{{cite journal| author=Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y et al.| title=Diagnosis and management of insulinoma. | journal=World J Gastroenterol | year= 2013 | volume= 19 | issue= 6 | pages= 829-37 | pmid=23430217 | doi=10.3748/wjg.v19.i6.829 | pmc=PMC3574879 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23430217 }} </ref> | The medical therapy of insulinoma include:<ref name="pmid23430217">{{cite journal| author=Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y et al.| title=Diagnosis and management of insulinoma. | journal=World J Gastroenterol | year= 2013 | volume= 19 | issue= 6 | pages= 829-37 | pmid=23430217 | doi=10.3748/wjg.v19.i6.829 | pmc=PMC3574879 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23430217 }} </ref><ref>[http://www.cancer.gov/cancertopics/pdq/treatment/isletcell/HealthProfessional/page6]</ref><ref>[http://www.nci.nih.gov/cancertopics/pdq/treatment/isletcell/Patient/page5]</ref> | ||
*[[Octreotide]] | *[[Octreotide]] | ||
*[[Endoscopic ultrasound]] guided alcohol ablation | *[[Endoscopic ultrasound]] guided alcohol ablation | ||
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*[[Diazoxide]] | *[[Diazoxide]] | ||
*[[Chemotherapy|Combination chemotherapy]] | *[[Chemotherapy|Combination chemotherapy]] | ||
**[[Doxorubicin]] {{ | **[[Doxorubicin]] {{and}} Streptozotocin | ||
**[[Fluorouracil]] {{and}} Streptozotocin (when [[doxorubicin]] is contraindicated) | |||
==References== | ==References== | ||
Revision as of 23:23, 7 October 2015
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [3]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [4]
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Overview
The predominant therapy for insulinoma is surgical resection. Supportive therapy for insulinoma includes octerotide, endoscopic ultrasound guided alcohol ablation, radiofrequency ablation, embolization, diazoxide and chemotherapy.
Medical Therapy
The medical therapy of insulinoma include:[1][2][3]
- Octreotide
- Endoscopic ultrasound guided alcohol ablation
- Radiofrequency ablation (RFA)
- Embolization
- Diazoxide
- Combination chemotherapy
- Doxorubicin AND Streptozotocin
- Fluorouracil AND Streptozotocin (when doxorubicin is contraindicated)
References