Hypopharyngeal cancer pathophysiology

Hypopharyngeal cancer Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]

Associated Diseases

Hypopharyngeal carcinoma is associated with:

• Sideropaenic dysphagia
• Paterson Brown Kelly syndrome

Gross Pathology

Gross pathology of hypopharyngeal cancer includes:

• Flattened plaques
• Raised margins of the lesion
• Mucosal ulceration
• Tumor spread to piriform sinus

Microscopic Pathology

Microscopic features of hypopharyngeal carcinoma include:

• Spindle cells
• Basaloid cells
• Nuclear atypia
• Abundant chromatin