Hypopharyngeal cancer pathophysiology: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
==Genetics== | ==Genetics== | ||
Genes involved in the pathogenesis of hypopharyngeal cancer include: | |||
*''p16'' | |||
*''NOTCH1'' | |||
*''cyclin D1'' | |||
*''TP53'' | |||
==Associated Diseases== | ==Associated Diseases== | ||
Hypopharyngeal carcinoma is associated with: | Hypopharyngeal carcinoma is associated with: | ||
Revision as of 14:31, 8 October 2015
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Hypopharyngeal cancer Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hypopharyngeal cancer pathophysiology On the Web |
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American Roentgen Ray Society Images of Hypopharyngeal cancer pathophysiology |
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Risk calculators and risk factors for Hypopharyngeal cancer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2]
Overview
Pathophysiology
Genetics
Genes involved in the pathogenesis of hypopharyngeal cancer include:
- p16
- NOTCH1
- cyclin D1
- TP53
Associated Diseases
Hypopharyngeal carcinoma is associated with:
- Sideropaenic dysphagia
- Paterson Brown Kelly syndrome
Gross Pathology
Gross pathology of hypopharyngeal cancer includes:
- Flattened plaques
- Raised margins of the lesion
- Mucosal ulceration
- Tumor spread to piriform sinus
Microscopic Pathology
Microscopic features of hypopharyngeal carcinoma include:
- Spindle cells
- Basaloid cells
- Nuclear atypia
- Abundant chromatin