Hepatoblastoma risk factors: Difference between revisions

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==Overview==
==Overview==
==Risk Factors==
==Risk Factors==
Risk factors for hepatoblastoma including the following:
* Being male.
* Being male.
* Having [[familial adenomatous polyposis]] (FAP).
* Having [[Beckwith-Wiedemann syndrome]].
* Having had a very low weight at birth.
The table below lists risk factors for hepatoblastoma:<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref>
The table below lists risk factors for hepatoblastoma:<ref name=risk>Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref>


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Aicardi syndrome'''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Aicardi syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:* Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies.
:* Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies.


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|-


| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Beckwith-Wiedemann syndrome'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Beckwith-Wiedemann syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:* Hemihypertrophy, hemihyperplasia.
:* Hemihypertrophy, hemihyperplasia.
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|-




| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Familial adenomatous polyposis'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Familial adenomatous polyposis]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*  
:*  
|-
|-


| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Glycogen storage diseases I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Glycogen storage diseases]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*Symptoms vary by individual disorder.
:*Symptoms vary by individual disorder.


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Simpson-Golabi-Behmel syndrome'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Simpson-Golabi-Behmel syndrome]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
:*Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of Wilms tumor.
:*Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of [[Wilms tumor]].


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|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Trisomy 18, other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" |
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Trisomy 18, other trisomies'''|| style="padding: 5px 5px; background: #F5F5F5;" |
:*Trisomy 18: Microcephaly and micrognathia, clenched fists with overlapping fingers, and failure to thrive. Most patients (>90%) die in the first month of life.
:*[[Trisomy 18]]: [[Microcephaly]] and [[micrognathia]], clenched fists with overlapping fingers, and failure to thrive. Most patients (>90%) die in the first month of life.


|}
|}
==References==
==References==
{{reflist|2}}
{{reflist|1}}


[[Category:Disease]]
[[Category:Disease]]

Revision as of 13:39, 28 October 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]

Overview

Risk Factors

  • Being male.

The table below lists risk factors for hepatoblastoma:[1]

Associated Disorder Clinical findings
Aicardi syndrome
  • Agenesis of the corpus callosum, chorioretinal lacunae, and infantile spasms, with a characteristic facies.
Beckwith-Wiedemann syndrome
  • Hemihypertrophy, hemihyperplasia.
Familial adenomatous polyposis
Glycogen storage diseases I–IV
  • Symptoms vary by individual disorder.
Low-birth-weight infants
  • Preterm and small-for-gestation-age neonates.
Simpson-Golabi-Behmel syndrome
  • Macroglossia, macrosomia, renal and skeletal abnormalities, and increased risk of Wilms tumor.
Trisomy 18, other trisomies

References

  1. Risk factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015


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