Uveal melanoma laboratory tests: Difference between revisions
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Revision as of 17:33, 27 November 2017
Uveal melanoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Some patients with uveal melanoma may have elevated concentration of complete and differential blood counts and elevated liver enzyme levels, which is usually suggestive of metastasis of uveal melanoma to the liver.[1]
Laboratory Tests
CBC
Liver function tests
Liver function tests include checking for serum levels of lactate dehydrogenase, gamma-glutamyl transpeptidase, alkaline phosphatase, and glutamic-oxaloacetic transaminase. These tests can be elevated in uveal melanoma that has metastasized to the liver. The following tests may be done on the sample of tissue to get more information about prognosis of uveal melanoma:[1]
Cytogenetic analysis
A laboratory test in which cells in a sample of tissue are viewed under a microscope to look for certain changes in the chromosomes.
Gene expression profiling
A laboratory test in which cells in a sample of tissue are checked for certain types of RNA. A biopsy may result in retinal detachment which can can be repaired by surgery.
References
- ↑ 1.0 1.1 Uveal melanoma. National Cancer Institute(2015) http://www.cancer.gov/types/eye/hp/intraocular-melanoma-treatment-pdq Accessed on October 24 2015