Hepatoblastoma natural history: Difference between revisions
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==Natural History== | ==Natural History== | ||
==Complications== | ==Complications== | ||
Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include: | |||
* Erythrocytosis | |||
* Thrombocytosis | |||
* Hypocalcaemia | |||
* Isosexual precocious puberty | |||
* Hypoglycaemia | |||
==Prognosis== | ==Prognosis== | ||
* The 5-year survival rate of children with hepatoblastoma is approximately 70%.<ref name=risk>Prognosis and Prognostic Factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | * The 5-year survival rate of children with hepatoblastoma is approximately 70%.<ref name=risk>Prognosis and Prognostic Factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | ||
Revision as of 14:43, 4 November 2015
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Hepatoblastoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Hepatoblastoma natural history On the Web |
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American Roentgen Ray Society Images of Hepatoblastoma natural history |
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Risk calculators and risk factors for Hepatoblastoma natural history |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Faizan Sheraz, M.D. [2] Nawal Muazam M.D.[3]
Overview
Natural History
Complications
Paraneoplastic features of hepatoblastoma are not uncommon at presentation and include:
- Erythrocytosis
- Thrombocytosis
- Hypocalcaemia
- Isosexual precocious puberty
- Hypoglycaemia
Prognosis
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.[1]
- The table below lists prognosis of hepatoblastma based on staging:[2]
| Subtype | Description |
|---|---|
| Stage I |
|
| Stage II |
|
| Stage III |
|
| Stage IV |
|
Factors that Affect Prognosis (chance of recovery) and Treatment Options
- The 5-year survival rate of children with hepatoblastoma is approximately 70%.
- The prognosis (chance of recovery) and treatment options depend on the following:
- The stage of the cancer (the size of the tumor
- Whether it affects part or all of the liver
- Whether it has spread to other places in the body, such as the lungs).
- Whether the cancer can be removed completely by surgery.
- The type of liver cancer (hepatoblastoma or hepatocellular).
- Whether the cancer has just been diagnosed or has recurred.
- Prognosis may also depend on:
- Certain features of the cancer cell (determined microscopically).
- Whether the AFP blood levels go down after chemotherapy is initiated.
References
- ↑ Prognosis and Prognostic Factors. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015
- ↑ Treatment and prognosis of hepatoblastoma. Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/hepatoblastoma. Accessed on November 3, 2015