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==Overview==
==Overview==
Cancerous tumors of the bile ducts are usually slow-growing and do not spread (metastasize) quickly. However, many of these tumors are already advanced by the time they are found.
==Diseases with similar symptoms==
Cholangiocarcinoma must also be differentiated from other diseases that cause [[jaundice]], [[abdominal pain]], [[weight loss]], and [[fatigue]]:
*[[Gallbladder cancer]]


A cholangiocarcinoma may start anywhere along the bile ducts. These tumors block off the bile ducts.
*[[Hepatocellular Carcinoma]]


They affect both men and women. Most patients are older than 65.
*[[Pancreatic cancer]]


==Diseases with similar symptoms==
*[[Cholecystitis]] and choledochitis
Differential diagnosis is different according to whether the tumour is intra or extrahepatic and depending on the growth pattern.<ref name=radio>Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma</ref>
 
*Liver fluke infections
 
 
Cholangiocarcinoma must be differentiated from other diseases such as:<ref name=radio>Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma</ref>
For an intrahepatic mass-forming cholangiocarcinoma consider:
For an intrahepatic mass-forming cholangiocarcinoma consider:
*Liver metastases
*Liver metastases
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:*Intratumoural cysts do not communicate with the biliary tree
:*Intratumoural cysts do not communicate with the biliary tree
*Benign stricture
*Benign stricture
Other health problems may also cause similar symptoms. Diseases with similar symptoms are listed in the following:


Cholangiocarcinoma must be differentiated from other diseases that cause [[jaundice]], [[abdominal pain]], [[weight loss]], and [[fatigue]]:
*[[Gallbladder cancer]]
*[[Gallbladder cancer]]


Revision as of 20:45, 4 November 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Diseases with similar symptoms

Cholangiocarcinoma must also be differentiated from other diseases that cause jaundice, abdominal pain, weight loss, and fatigue:

  • Liver fluke infections


Cholangiocarcinoma must be differentiated from other diseases such as:[1] For an intrahepatic mass-forming cholangiocarcinoma consider:

  • Liver metastases
  • Central necrosis (high T2 signal) is more common
  • Hepatocellular carcinoma (HCC)
  • Tumor thrombus more common
  • Capsular retraction uncommon
  • May appear very similar
  • Other primary liver tumors
  • Hepatic abscess

For a periductal infiltrating cholangiocarcinoma consider:

  • Benign stricture
  • Usually short-segment
  • Regular margin
  • Symmetric narrowing
  • No ductal enhancement
  • No lymph node enlargement
  • No periductal soft-tissue mass
  • Periportal lymphangitic metastasis

For an intraductal cholangiocarcinoma consider:

  • Intraductal invasion by a HCC
  • Extraductal mass
  • Hepatolithiasis
  • No enhancement
  • Higher attenuation
  • Biliary cystadenoma or cystadenocarcinoma
  • Intratumoural cysts do not communicate with the biliary tree
  • Benign stricture

Cholangiocarcinoma must be differentiated from other diseases that cause jaundice, abdominal pain, weight loss, and fatigue:

  • Liver fluke infections

References

  1. ↑ Cholangiocarcinoma. Radiopaedia. http://radiopaedia.org/articles/cholangiocarcinoma

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