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Hepatic tumors represent approximately 0.5-2% of all the tumors in children and are responsible for 1-4% of all the solid tumors.<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | Hepatic tumors represent approximately 0.5-2% of all the tumors in children and are responsible for 1-4% of all the solid tumors.<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | ||
===Incidence=== | ===Incidence=== | ||
The annual incidence of hepatoblastoma in the United States appears to have doubled from | The annual incidence of hepatoblastoma in the United States appears to have doubled from 8 (1975-1983) to 16 (2002-2009) per 100,000 children aged 19 years and younger.<ref name=risk>Incidence. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015</ref> | ||
===Age=== | ===Age=== | ||
Hepatoblastoma is a common tumor that tends to affect children aged less than five years.<ref name="AllanParikh2013">{{cite journal|last1=Allan|first1=Bassan J.|last2=Parikh|first2=Punam P.|last3=Diaz|first3=Sofia|last4=Perez|first4=Eduardo A.|last5=Neville|first5=Holly L.|last6=Sola|first6=Juan E.|title=Predictors of survival and incidence of hepatoblastoma in the paediatric population|journal=HPB|volume=15|issue=10|year=2013|pages=741–746|issn=1365182X|doi=10.1111/hpb.12112}}</ref> Approximately 90% of the cases occur in patients under 5 years of age and two-thirds of the cases occur in the first 2 years of life. Hepatoblastoma in adolescents and young adults is extremely rare.<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | Hepatoblastoma is a common tumor that tends to affect children aged less than five years.<ref name="AllanParikh2013">{{cite journal|last1=Allan|first1=Bassan J.|last2=Parikh|first2=Punam P.|last3=Diaz|first3=Sofia|last4=Perez|first4=Eduardo A.|last5=Neville|first5=Holly L.|last6=Sola|first6=Juan E.|title=Predictors of survival and incidence of hepatoblastoma in the paediatric population|journal=HPB|volume=15|issue=10|year=2013|pages=741–746|issn=1365182X|doi=10.1111/hpb.12112}}</ref> Approximately 90% of the cases occur in patients under 5 years of age and two-thirds of the cases occur in the first 2 years of life. Hepatoblastoma in adolescents and young adults is extremely rare.<ref name="MadabhaviPatel2014">{{cite journal|last1=Madabhavi|first1=Irappa|last2=Patel|first2=Apurva|last3=Choudhary|first3=Mukesh|last4=Aagre|first4=Suhas|last5=Revannasiddaiah|first5=Swaroop|last6=Modi|first6=Gaurang|last7=Anand|first7=Asha|last8=Panchal|first8=Harsha|last9=Parikh|first9=Sonia|last10=Raut|first10=Shreeniwas|title=Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity|journal=Case Reports in Pediatrics|volume=2014|year=2014|pages=1–5|issn=2090-6803|doi=10.1155/2014/104543}}</ref> | ||
Revision as of 19:53, 13 November 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
Hepatoblastoma is a common tumor that tends to affect children aged less than five years.[1] Males are more commonly affected with hepatoblastoma than females. [2] The annual incidence of hepatoblastoma in the United States appears to have doubled from 8 (1975-1983) to 16 (2002-2009) per 100,000 children aged 19 years and younger.[3]
Epidemiology and demographics
Prevalence
Hepatic tumors represent approximately 0.5-2% of all the tumors in children and are responsible for 1-4% of all the solid tumors.[4]
Incidence
The annual incidence of hepatoblastoma in the United States appears to have doubled from 8 (1975-1983) to 16 (2002-2009) per 100,000 children aged 19 years and younger.[3]
Age
Hepatoblastoma is a common tumor that tends to affect children aged less than five years.[1] Approximately 90% of the cases occur in patients under 5 years of age and two-thirds of the cases occur in the first 2 years of life. Hepatoblastoma in adolescents and young adults is extremely rare.[4]
Gender
Males are more commonly affected with hepatoblastoma than females.[2]
References
- ↑ 1.0 1.1 Allan, Bassan J.; Parikh, Punam P.; Diaz, Sofia; Perez, Eduardo A.; Neville, Holly L.; Sola, Juan E. (2013). "Predictors of survival and incidence of hepatoblastoma in the paediatric population". HPB. 15 (10): 741–746. doi:10.1111/hpb.12112. ISSN 1365-182X.
- ↑ 2.0 2.1 Epidemiology of hepatoblastoma. Dr Frank Gaillard et al. Radiopaedia 2015. http://radiopaedia.org/articles/hepatoblastoma. Accessed on November 6, 2015
- ↑ 3.0 3.1 Incidence. National Cancer Institute 2015. http://www.cancer.gov/types/liver/hp/child-liver-treatment-pdq#link/_570_toc. Accessed on October 28, 2015
- ↑ 4.0 4.1 Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.