Hepatoblastoma medical therapy: Difference between revisions
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*[[Chemotherapy]] has been proven effective in both an [[adjuvant]] and [[neoadjuvant]] treatment and can shrink tumors. | *[[Chemotherapy]] has been proven effective in both an [[adjuvant]] and [[neoadjuvant]] treatment and can shrink tumors. | ||
*It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections. | *It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections. | ||
*Hepatoblastoma is sensitive to such chemotherapy drugs as [[doxorubicin]], [[cisplatin]], [[vincristine]], [[5-Fluorouracil]] and [[cyclophosphamide]]. | *Hepatoblastoma is sensitive to such chemotherapy drugs as [[doxorubicin]], [[cisplatin]], [[vincristine]], [[5-Fluorouracil]], and [[cyclophosphamide]]. | ||
==References== | ==References== | ||
{{reflist|1}} | {{reflist|1}} | ||
Revision as of 22:16, 13 November 2015
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Hepatoblastoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Nawal Muazam M.D.[2]
Overview
The predominant therapy for hepatoblastoma is surgical resection. Neoadjuvant and adjuvant chemotherapy may be required.[1]
Medical Therapy
Adjuvant chemotherapy prior to resection have been used to treat hepatoblastoma.[1]
- Chemotherapy has been proven effective in both an adjuvant and neoadjuvant treatment and can shrink tumors.
- It makes them less prone to bleed and delineates the tumor from the surrounding normal parenchyma and vascular structures so as to facilitate the resections.
- Hepatoblastoma is sensitive to such chemotherapy drugs as doxorubicin, cisplatin, vincristine, 5-Fluorouracil, and cyclophosphamide.
References
- ↑ 1.0 1.1 Madabhavi, Irappa; Patel, Apurva; Choudhary, Mukesh; Aagre, Suhas; Revannasiddaiah, Swaroop; Modi, Gaurang; Anand, Asha; Panchal, Harsha; Parikh, Sonia; Raut, Shreeniwas (2014). "Paraneoplastic Recurrent Hypoglycaemic Seizures: An Initial Presentation of Hepatoblastoma in an Adolescent Male—A Rare Entity". Case Reports in Pediatrics. 2014: 1–5. doi:10.1155/2014/104543. ISSN 2090-6803.