Anaplastic thyroid cancer pathophysiology: Difference between revisions
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==Pathogenesis== | ==Pathogenesis== | ||
* Anaplastic tumors have a high mitotic rate and lymphovascular invasion. It rapidly invades surrounding tissues (such as the trachea). The presence of regional lymphadenopathy in older patients in whomneedle aspiration biopsy reveals characteristic vesicular appearance of the nuclei would support a diagnosis of anaplastic carcinoma. | * Anaplastic tumors have a high mitotic rate and lymphovascular invasion. It rapidly invades surrounding tissues (such as the trachea). The presence of regional lymphadenopathy in older patients in whomneedle aspiration biopsy reveals characteristic vesicular appearance of the nuclei would support a diagnosis of anaplastic carcinoma. Most cases of anaplastic thyroid cancer have distant metastasis at the time of diagnosis because of the rapid growth and aggressive nature of this type of cancer. Common sites of metastasis include the lungs, pleurapleuraThe thin layer of tissue that covers the lungs and lines the chest cavity. It protects and cushions the lungs and produces a fluid that acts like a lubricant so the lungs can move smoothly in the chest cavity., bones and brain. | ||
* It is always considered as stage IV. | * It is always considered as stage IV. | ||
==Genetics== | ==Genetics== | ||
Revision as of 16:20, 19 November 2015
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Anaplastic thyroid cancer Microchapters |
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Differentiating Anaplastic thyroid cancer from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Anaplastic thyroid cancer pathophysiology On the Web |
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American Roentgen Ray Society Images of Anaplastic thyroid cancer pathophysiology |
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Risk calculators and risk factors for Anaplastic thyroid cancer pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]
Overview
Pathogenesis
- Anaplastic tumors have a high mitotic rate and lymphovascular invasion. It rapidly invades surrounding tissues (such as the trachea). The presence of regional lymphadenopathy in older patients in whomneedle aspiration biopsy reveals characteristic vesicular appearance of the nuclei would support a diagnosis of anaplastic carcinoma. Most cases of anaplastic thyroid cancer have distant metastasis at the time of diagnosis because of the rapid growth and aggressive nature of this type of cancer. Common sites of metastasis include the lungs, pleurapleuraThe thin layer of tissue that covers the lungs and lines the chest cavity. It protects and cushions the lungs and produces a fluid that acts like a lubricant so the lungs can move smoothly in the chest cavity., bones and brain.
- It is always considered as stage IV.