Atypical teratoid rhabdoid tumor diagnostic criteria: Difference between revisions

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Revision as of 19:57, 14 December 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

The diagnosis of atypical teratoid rhabdoid tumor is based on the current WHO classification of tumors of the CNS criteria, which include:

Presence of rhabdoid tumor cells and/or divergent differentiation along epithelial, mesenchymal, neuronal, or glial lines

AND

Complete loss of SMARCB1 protein expression in tumor cell nuclei, but expression retained in preexisting cells (e.g., endothelial cells)

@@ Line 6: / Line 6: @@
 ==Diagnostic Criteria==
+The diagnosis of atypical teratoid rhabdoid tumor is based on the current WHO classification of tumors of the CNS criteria, which include:
+*Presence of rhabdoid tumor cells and/or divergent differentiation along [[epithelial]], [[mesenchymal]], [[neuronal]], or [[glial|glial lines]]
+:{{and}}
+*Complete loss of [[SMARCB1]] protein expression in tumor cell nuclei, but expression retained in preexisting cells (e.g., [[endothelial cells]])
 ==References==